Substrate: GSK-3 beta (Glycogen synthase kinase-3 beta)
Seq-ID: P49841 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-65985   DBPA_HUMAN
MINT-65986   YBOX1_HUMAN
MINT-2837737   PSN1_HUMAN
MINT-3974216   TAU_HUMAN
MINT-4049759   PCM1_HUMAN
MINT-4049773   NIN_HUMAN
MINT-4508051   CTNB1_HUMAN
MINT-4508259   AXN1_HUMAN
MINT-4793253   P53_HUMAN
MINT-6761890   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
tau-protein kinase activity,
p53 binding,
beta-catenin binding,
ATP binding,
protein kinase A catalytic subunit binding,
NF-kappaB binding		 Axin-APC-beta-catenin-GSK3B complex,
beta-catenin destruction complex,
cytosol,
nucleus		 positive regulation of protein catabolic process,
hippocampus development,
negative regulation of apoptosis,
positive regulation of protein export from nucleus,
positive regulation of Rac GTPase activity,
positive regulation of protein complex assembly,
peptidyl-serine phosphorylation,
glycogen metabolic process,
superior temporal gyrus development,
canonical Wnt receptor signaling pathway,
ER overload response,
negative regulation of protein binding,
positive regulation of cell-matrix adhesion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 7     MSGRPRTTSFAESCKPV - 18669648
HTP
0.68
 - -
0.61
 --
S 9   MSGRPRTTSFAESCKPVQQ PKA_group 11035810
LTP
0.60
 MOD_PKA_2
 - -
0.61
 --
S 9   MSGRPRTTSFAESCKPVQQ RSK_group 16039586
LTP
0.60
 MOD_PKA_2
 - -
0.61
 --
S 9   MSGRPRTTSFAESCKPVQQ - 17192257
HTP
0.60
 MOD_PKA_2
 - -
0.61
 --
S 9   MSGRPRTTSFAESCKPVQQ - 18669648
HTP
0.60
 MOD_PKA_2
 - -
0.61
 --
S 21 AESCKPVQQPSAFGSMKVSRD SGK_group 12054501
LTP
0.24
 - -
0.47
 --
T 43 DGSKVTTVVATPGQGPDRPQE MAPK1 16039586
LTP
0.83
 MOD_ProDKin_1
 - -
0.66
 1Q5K 12.33%
T 43 DGSKVTTVVATPGQGPDRPQE MAPK3 16039586
LTP
0.83
 MOD_ProDKin_1
 - -
0.66
 1Q5K 12.33%
Y 216 QLVRGEPNVSYICSRYYRAPE MAP2K1 15020233
LTP
1.00
 - S_TKc
0.08
 1Q5K 79.91%
Y 216 QLVRGEPNVSYICSRYYRAPE - 17081983
HTP
1.00
 - S_TKc
0.08
 1Q5K 79.91%
Y 216 QLVRGEPNVSYICSRYYRAPE - 17192257
HTP
1.00
 - S_TKc
0.08
 1Q5K 79.91%
Y 216 QLVRGEPNVSYICSRYYRAPE - 16964243
HTP
1.00
 - S_TKc
0.08
 1Q5K 79.91%
Y 216 QLVRGEPNVSYICSRYYRAPE - 18083107
HTP
1.00
 - S_TKc
0.08
 1Q5K 79.91%
Y 216 QLVRGEPNVSYICSRYYRAPE - 18669648
HTP
1.00
 - S_TKc
0.08
 1Q5K 79.91%
T 390 PHARIQAAASTPTNATAASDA - 17192257
HTP
0.15
 - -
0.72
 --
T 390 PHARIQAAASTPTNATAASDA - 18669648
HTP
0.15
 - -
0.72
 --
T 392 ARIQAAASTPTNATAASDANT - 18669648
HTP
0.31
 - -
0.76
 --
T 402 TNATAASDANTGDRGQTNNAA - 15302935
HTP
0.16
 - -
0.85
 --

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