Substrate: Vav 2 (Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases)
Seq-ID: P52735 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-74802   ERBB2_HUMAN
MINT-74803   ERBB3_HUMAN
MINT-7301276   3BP2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Rho guanyl-nucleotide exchange factor activity,
metal ion binding		 cytosol induction of apoptosis by extracellular signals,
angiogenesis,
apoptosis,
regulation of Rho protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 142 EETTENDDDVYRSLEELADEH Lck 12454019
LTP
1.00
 - -
0.54
 - low
Y 142 EETTENDDDVYRSLEELADEH EGFR 12454019
LTP
1.00
 - -
0.54
 - low
Y 159 ADEHDLGEDIYDCVPCEDGGD Lck 12454019
LTP
0.04
 - -
0.31
 - low
Y 159 ADEHDLGEDIYDCVPCEDGGD EGFR 12454019
LTP
0.04
 - -
0.31
 - low
Y 172 VPCEDGGDDIYEDIIKVEVQQ Lck 12454019
LTP
1.00
 - -
0.25
 - low
Y 172 VPCEDGGDDIYEDIIKVEVQQ EGFR 12454019
LTP
1.00
 - -
0.25
 - low
T 575 CLEVIPPCKFTSPADLDASGA - 18669648
HTP
0.73
 - C1_1
0.33
 - low
S 576 LEVIPPCKFTSPADLDASGAG - 18669648
HTP
0.11
 - -
0.36
 - low
S 779 SRERSASRASSRSPASCASYN - 18669648
HTP
0.75
 - -
0.38
 - low
S 781 ERSASRASSRSPASCASYNFS - 18669648
HTP
0.23
 - -
0.31
 - low

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