Substrate: Bloom syndrome protein (Enzyme: DNA helicase)
Seq-ID: P54132 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
G-quadruplex DNA binding,
ATP-dependent 3`-5` DNA helicase activity,
DNA strand annealing activity,
p53 binding,
ATP binding,
bubble DNA binding,
four-way junction helicase activity		 cytoplasm,
lateral element,
nucleolus,
nuclear matrix,
PML body		 replication fork processing,
G2 phase of mitotic cell cycle,
positive regulation of transcription,
regulation of cyclin-dependent protein kinase activity,
replication fork protection,
G2/M transition DNA damage checkpoint,
protein oligomerization,
response to X-ray,
double-strand break repair via homologous recombination,
negative regulation of cell division
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 48 KKKTSSDNNVSVTNVSVAKTP - 18669648
HTP
0.21
 - -
0.56
 - medium
S 53 SDNNVSVTNVSVAKTPVLRNK - 18669648
HTP
0.04
 - -
0.57
 - medium
T 57 VSVTNVSVAKTPVLRNKDVNV - 18669648
HTP
0.04
 - -
0.52
 - medium
S 72 NKDVNVTEDFSFSEPLPNTTN - 18669648
HTP
0.05
 - -
0.62
 - medium
T 99 FFKNAPAGQETQRGGSKSLLP ATM 11375976
LTP
0.10
 MOD_PIKK_1
 - -
0.63
 - medium
T 114 SKSLLPDFLQTPKEVVCTTQN - 18669648
HTP
0.13
 - -
0.49
 - medium
T 122 LQTPKEVVCTTQNTPTVKKSR - 14729972
LTP
0.14
 - -
0.61
 - medium
S 142 RDTALKKLEFSSSPDSLSTIN - 18669648
HTP
0.18
 - -
0.49
 - medium
S 144 TALKKLEFSSSPDSLSTINDW - 16864798
LTP
0.93
 - -
0.48
 - medium
S 144 TALKKLEFSSSPDSLSTINDW - 18669648
HTP
0.93
 - -
0.48
 - medium
S 358 MSMQELNPETSTDCDARQISL - 18669648
HTP
0.34
 - -
0.66
 - medium
T 412 QQRNIRRKLLTEVDFNKSDAS - 18669648
HTP
0.00
 - -
0.36
 - medium
S 419 KLLTEVDFNKSDASLLGSLWR - 16565220
HTP
0.66
 - -
0.23
 - medium
S 419 KLLTEVDFNKSDASLLGSLWR - 18669648
HTP
0.66
 - -
0.23
 - medium
S 422 TEVDFNKSDASLLGSLWRYRP - 16565220
HTP
0.05
 - -
0.25
 - medium
S 422 TEVDFNKSDASLLGSLWRYRP - 18669648
HTP
0.05
 - -
0.25
 - medium
S 499 RPLFNTHLQKSFVSSNWAETP - 16964243
HTP
0.11
 - -
0.36
 - medium
T 508 KSFVSSNWAETPRLGKKNESS - 16964243
HTP
0.05
 - -
0.46
 - medium
S 550 INDLERETQPSYDIDNFDIDD - 18669648
HTP
0.11
 - -
0.48
 - medium
Y 551 NDLERETQPSYDIDNFDIDDF - 18669648
HTP
0.77
 - -
0.49
 - medium
S 1295 YSEWTSPAEDSSPGISLSSSR - 18669648
HTP
0.45
 - -
0.59
 - medium
S 1296 SEWTSPAEDSSPGISLSSSRG - 15302935
HTP
0.23
 - -
0.63
 - medium
S 1296 SEWTSPAEDSSPGISLSSSRG - 18669648
HTP
0.23
 - -
0.63
 - medium
S 1303 EDSSPGISLSSSRGPGRSAAE - 18669648
HTP
0.30
 - -
0.70
 - medium
S 1304 DSSPGISLSSSRGPGRSAAEE - 18669648
HTP
0.30
 - -
0.69
 - medium
S 1310 SLSSSRGPGRSAAEELDEEIP - 18669648
HTP
0.37
 - -
0.65
 - medium

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