Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Grb2 (Adaptor molecule)

Seq-ID:

P62993 [Homo sapiens]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-14744   RPGF1_HUMAN
MINT-49659   A4_HUMAN
MINT-50656   MAP2_HUMAN
MINT-58395   GAB1_HUMAN
MINT-60975   RET_HUMAN
MINT-61518   ERBB3_HUMAN
MINT-61534   ERBB4_HUMAN
MINT-61537   SHC1_HUMAN
MINT-61540   EGFR_HUMAN
MINT-61541   IQGA1_HUMAN
MINT-61542   RGAP1_HUMAN
MINT-61546   AP2B1_HUMAN
MINT-61548   AP2M1_HUMAN
MINT-61549   CBLB_HUMAN
MINT-61552   PTN11_HUMAN
MINT-61554   K2C7_HUMAN
MINT-61555   K2C8_HUMAN
MINT-61556   K1C17_HUMAN
MINT-61557   K1C18_HUMAN
MINT-61558   PLEC1_HUMAN
MINT-61559   EPIPL_HUMAN
MINT-61561   H31_HUMAN
MINT-61562   SMD2_HUMAN
MINT-62810   BAT2_HUMAN
MINT-62876   ACK1_HUMAN
MINT-65952   DYN1_HUMAN
MINT-65974   P85A_HUMAN
MINT-74542   ERBB2_HUMAN
MINT-2516705   DYN2_HUMAN
MINT-2792931   PAK2_HUMAN
MINT-3381238   VGFR2_HUMAN
MINT-3382436   LAT_HUMAN
MINT-6169717   SPY1_HUMAN
MINT-6169734   SPY2_HUMAN
MINT-6169976   SOS1_MOUSE
MINT-6170118   SOS1_HUMAN
MINT-6762786   IRS1_RAT
MINT-6794792   PTN1_HUMAN
MINT-7040249   CBL_HUMAN
MINT-7144603   BLNK_HUMAN
MINT-7212968   M4K1_HUMAN
MINT-7218139   ADA15_HUMAN
MINT-7219650   CDN1B_HUMAN
MINT-7220613   GAB2_HUMAN
MINT-7253206   FANCA_HUMAN
MINT-7253218   ABL1_HUMAN
MINT-7253230   FLNB_HUMAN
MINT-7253290   FLNA_HUMAN
MINT-7253314   FLNC_HUMAN
MINT-7253338   RRAS_HUMAN
MINT-7253374   SHAN2_HUMAN
MINT-7253410   PHAR2_HUMAN
MINT-7253470   DLGP4_HUMAN
MINT-7253494   TGON2_HUMAN
MINT-7253518   ICAL_HUMAN
MINT-7253542   KI13A_HUMAN
MINT-7253590   SHRM2_HUMAN
MINT-7253662   SUV92_HUMAN
MINT-7253674   ARHGB_HUMAN
MINT-7253686   AKAP2_HUMAN
MINT-7253698   SNX3_HUMAN
MINT-7253734   ASAP1_HUMAN
MINT-7253770   PTN13_HUMAN
MINT-7253782   ABL2_HUMAN
MINT-7253806   BAZ2A_HUMAN
MINT-7253818   TRAIP_HUMAN
MINT-7253842   TAL2_HUMAN
MINT-7306657   LCP2_HUMAN
MINT-7980585   TM1L1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
epidermal growth factor receptor binding, insulin receptor substrate binding, SH3/SH2 adaptor activity	cytosol, Golgi apparatus	epidermal growth factor receptor signaling pathway, cell-cell signaling, interspecies interaction between organisms, Ras protein signal transduction, insulin receptor signaling pathway, receptor internalization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	209	HGQTGMFPRNYVTPVNRNV	EGFR	11726515	LTP	1.00		-	SH3	0.39	2VWF	35.37%
T	211	QTGMFPRNYVTPVNRNV	-	18669648	HTP	0.07		-	SH3	0.37	2VWF	40.41%