Substrate: SMAD4 (Transcription factor)
Seq-ID: P97471 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
MINT-49782   LAP2_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription activator activity,
collagen binding,
chromatin binding,
sequence-specific DNA binding transcription factor activity		 cytoplasm branching involved in ureteric bud morphogenesis,
regulation of binding,
positive regulation of pathway-restricted SMAD protein phosphorylation,
transcription,
gastrulation with mouth forming second,
negative regulation of cell death,
negative regulation of cell proliferation,
neuron fate commitment,
formation of anatomical boundary,
mesoderm development,
nephrogenic mesenchyme morphogenesis,
in utero embryonic development,
endoderm development,
transforming growth factor beta receptor signaling pathway,
developmental growth,
palate development,
positive regulation of transcription from RNA polymerase II promoter,
positive regulation of SMAD protein nuclear translocation,
cell proliferation,
metanephric mesenchyme morphogenesis,
positive regulation of epithelial to mesenchymal transition,
somite rostral/caudal axis specification
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 276 TWTGSRTAPYTPNLPHHQNGH MAPK1 12801888
LTP
0.91
 MOD_ProDKin_1
 - -
0.77
 - medium

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