Substrate: Glutamate [NMDA] receptor subunit epsilon 2 (Extracellular ligand gated channel)
Seq-ID: Q00960 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-60072   DLG2_RAT
MINT-60074   DLG4_RAT
MINT-1890944   DLG4_MOUSE
MINT-1891205   INADL_MOUSE
MINT-2841984   KCC2A_MOUSE
MINT-3377699   SRC_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cell adhesion molecule binding,
zinc ion binding,
drug binding,
D2 dopamine receptor binding,
neurotransmitter binding,
protein heterodimerization activity,
ionotropic glutamate receptor binding,
N-methyl-D-aspartate selective glutamate receptor activity,
beta-catenin binding,
extracellular-glutamate-gated ion channel activity		 N-methyl-D-aspartate selective glutamate receptor complex,
cell junction,
synaptic cleft,
flotillin complex,
terminal button,
postsynaptic membrane,
postsynaptic density,
Z disc,
dendritic spine,
presynaptic membrane,
outer membrane-bounded periplasmic space		 response to amphetamine,
regulation of action potential,
hippocampus development,
long-term memory,
response to growth hormone stimulus,
response to magnesium ion,
cellular response to organic cyclic substance,
cellular response to amino acid stimulus,
response to methylmercury,
regulation of MAPKKK cascade,
response to cytokine stimulus,
response to fungicide,
cellular response to lipid,
response to electrical stimulus,
regulation of long-term neuronal synaptic plasticity,
cellular response to growth factor stimulus,
cerebral cortex development,
response to ethanol,
associative learning,
cellular response to dsRNA,
rhythmic process,
response to carbohydrate stimulus,
cellular response to manganese ion,
cellular response to protein stimulus,
response to cocaine,
cellular response to magnesium starvation,
ionotropic glutamate receptor signaling pathway,
positive regulation of glutamate secretion,
receptor clustering,
positive regulation of synaptic transmission,
response to calcium ion,
response to other organism,
positive regulation of cell death
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 383 WERVGKWKDKSLQMKYYVWPR CaM-KII_group 8940188
LTP
1.00
 - -
0.11
 - medium
S 1303 KNRNKLRRQHSYDTFVDLQKE CaM-KII_group 12147342
LTP
1.00
 - NMDAR2_C
0.57
 - medium
S 1303 KNRNKLRRQHSYDTFVDLQKE CaM-KII_group 8940188
LTP
1.00
 - NMDAR2_C
0.57
 - medium
Y 1472 AFNGSSNGHVYEKLSSIESDV SRC 11483655
LTP
1.00
 - NMDAR2_C
0.43
 - medium

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