Substrate: DNA topoisomerase II, beta (Enzyme: Topoisomerase)
Seq-ID: Q02880 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase C binding,
DNA topoisomerase (ATP-hydrolyzing) activity,
protein heterodimerization activity,
protein C-terminus binding,
chromatin binding,
histone deacetylase binding,
ATP binding		 SWI/SNF-type complex,
cytosol,
chromosome,
nucleolus,
nucleoplasm		 DNA topological change
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 639 WKIKYYKGLGTSTAKEAKEYF - 17081983
HTP
1.00
 - TOP2c
0.17
 - low
S 640 KIKYYKGLGTSTAKEAKEYFA - 17081983
HTP
1.00
 - TOP2c
0.16
 - low
S 1236 KKLQLEETMPSPYGRRIIPEI - 18669648
HTP
0.92
 - -
0.54
 - low
S 1336 AKKVKKRNPWSDDESKSESDL - 17081983
HTP
0.85
 - -
0.76
 - low
S 1336 AKKVKKRNPWSDDESKSESDL - 18669648
HTP
0.85
 - -
0.76
 - low
S 1340 KKRNPWSDDESKSESDLEETE - 17081983
HTP
0.75
 - -
0.80
 - low
S 1340 KKRNPWSDDESKSESDLEETE - 18669648
HTP
0.75
 - -
0.80
 - low
S 1342 RNPWSDDESKSESDLEETEPV - 17081983
HTP
0.15
 - -
0.81
 - low
S 1342 RNPWSDDESKSESDLEETEPV - 18669648
HTP
0.15
 - -
0.81
 - low
S 1344 PWSDDESKSESDLEETEPVVI - 17081983
HTP
0.69
 - -
0.81
 - low
S 1344 PWSDDESKSESDLEETEPVVI - 18669648
HTP
0.69
 - -
0.81
 - low
Y 1370 LRRAAAERPKYTFDFSEEEDD - 18669648
HTP
0.68
 - -
0.67
 - low
S 1375 AERPKYTFDFSEEEDDDADDD - 18669648
HTP
0.81
 - -
0.79
 - low
S 1400 NDLEELKVKASPITNDGEDEF - 17081983
HTP
0.12
 - -
0.74
 - low
S 1400 NDLEELKVKASPITNDGEDEF - 18220336
HTP
0.12
 - -
0.74
 - low
S 1400 NDLEELKVKASPITNDGEDEF - 18669648
HTP
0.12
 - -
0.74
 - low
S 1413 TNDGEDEFVPSDGLDKDEYTF - 17081983
HTP
0.48
 - -
0.71
 - low
S 1413 TNDGEDEFVPSDGLDKDEYTF - 18220336
HTP
0.48
 - -
0.71
 - low
S 1413 TNDGEDEFVPSDGLDKDEYTF - 18669648
HTP
0.48
 - -
0.71
 - low
Y 1421 VPSDGLDKDEYTFSPGKSKAT - 18669648
HTP
0.00
 - -
0.70
 - low
T 1422 PSDGLDKDEYTFSPGKSKATP - 18669648
HTP
0.09
 - -
0.70
 - low
S 1424 DGLDKDEYTFSPGKSKATPEK - 18220336
HTP
0.44
 - -
0.73
 - low
S 1424 DGLDKDEYTFSPGKSKATPEK - 18669648
HTP
0.44
 - -
0.73
 - low
Y 1453 DFGNLFSFPSYSQKSEDDSAK - 18669648
HTP
 - - -
0.54
 - low
S 1454 FGNLFSFPSYSQKSEDDSAKF - 17525332
HTP
0.33
 - -
0.54
 - low
S 1454 FGNLFSFPSYSQKSEDDSAKF - 18669648
HTP
0.33
 - -
0.54
 - low
S 1457 LFSFPSYSQKSEDDSAKFDSN - 18669648
HTP
0.24
 - -
0.60
 - low
S 1461 PSYSQKSEDDSAKFDSNEEDS - 18669648
HTP
0.24
 - -
0.73
 - low
S 1466 KSEDDSAKFDSNEEDSASVFS - 18669648
HTP
0.13
 - -
0.72
 - low
S 1471 SAKFDSNEEDSASVFSPSFGL - 16565220
HTP
0.29
 - -
0.63
 - low
S 1471 SAKFDSNEEDSASVFSPSFGL - 18669648
HTP
0.29
 - -
0.63
 - low
S 1522 KQKKVVEAVNSDSDSEFGIPK - 15302935
HTP
0.53
 - DTHCT
0.67
 - low
S 1522 KQKKVVEAVNSDSDSEFGIPK - 17081983
HTP
0.53
 - DTHCT
0.67
 - low
S 1522 KQKKVVEAVNSDSDSEFGIPK - 18669648
HTP
0.53
 - DTHCT
0.67
 - low
S 1524 KKVVEAVNSDSDSEFGIPKKT - 16565220
HTP
0.44
 - DTHCT
0.68
 - low
S 1524 KKVVEAVNSDSDSEFGIPKKT - 17081983
HTP
0.44
 - DTHCT
0.68
 - low
S 1524 KKVVEAVNSDSDSEFGIPKKT - 18669648
HTP
0.44
 - DTHCT
0.68
 - low
S 1526 VVEAVNSDSDSEFGIPKKTTT - 17081983
HTP
0.50
 - DTHCT
0.70
 - low
S 1526 VVEAVNSDSDSEFGIPKKTTT - 18669648
HTP
0.50
 - DTHCT
0.70
 - low
S 1550 KGRGAKKRKASGSENEGDYNP - 15302935
HTP
0.74
 - DTHCT
0.85
 - low
S 1550 KGRGAKKRKASGSENEGDYNP - 17081983
HTP
0.74
 - DTHCT
0.85
 - low
S 1550 KGRGAKKRKASGSENEGDYNP - 18669648
HTP
0.74
 - DTHCT
0.85
 - low
S 1552 RGAKKRKASGSENEGDYNPGR - 17081983
HTP
0.64
 - DTHCT
0.85
 - low
S 1552 RGAKKRKASGSENEGDYNPGR - 18669648
HTP
0.64
 - DTHCT
0.85
 - low
T 1575 SKTTSKKPKKTSFDQDSDVDI - 18220336
HTP
0.26
 - DTHCT
0.71
 - low
T 1575 SKTTSKKPKKTSFDQDSDVDI - 18669648
HTP
0.26
 - DTHCT
0.71
 - low
S 1576 KTTSKKPKKTSFDQDSDVDIF - 17081983
HTP
0.25
 - DTHCT
0.69
 - low
S 1576 KTTSKKPKKTSFDQDSDVDIF - 18669648
HTP
0.25
 - DTHCT
0.69
 - low
S 1581 KPKKTSFDQDSDVDIFPSDFP - 17081983
HTP
0.11
 - DTHCT
0.68
 - low
S 1581 KPKKTSFDQDSDVDIFPSDFP - 18220336
HTP
0.11
 - DTHCT
0.68
 - low
S 1581 KPKKTSFDQDSDVDIFPSDFP - 18669648
HTP
0.11
 - DTHCT
0.68
 - low
T 1592 DVDIFPSDFPTEPPSLPRTGR - 18669648
HTP
0.00
 - DTHCT
0.81
 - low
S 1596 FPSDFPTEPPSLPRTGRARKE - 18669648
HTP
0.09
 - DTHCT
0.81
 - low
Y 1609 RTGRARKEVKYFAESDEEEDD - 18669648
HTP
0.95
 - DTHCT
0.69
 - low
S 1613 ARKEVKYFAESDEEEDDVDFA - 18669648
HTP
0.95
 - -
0.58
 - low

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