Substrate: p65 (Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit), RelA)
Seq-ID: Q04206 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-50016   IKBA_MOUSE
MINT-50017   IKBB_MOUSE
MINT-50025   KAPCA_HUMAN
MINT-50073   KS6A5_HUMAN
MINT-50084   KPCZ_HUMAN
MINT-50090   CSK21_HUMAN
MINT-50107   IKKA_HUMAN
MINT-50167   IKKB_HUMAN
MINT-50171   HDAC1_HUMAN
MINT-50175   KAT2B_HUMAN
MINT-50178   EP300_HUMAN
MINT-50179   HDAC3_HUMAN
MINT-58638   NCF1_HUMAN
MINT-62399   TF2B_HUMAN
MINT-2834593   NCOA3_HUMAN
MINT-6166971   OGT1_HUMAN
MINT-7235700   ASPP2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription repressor activity,
transcription repressor binding,
identical protein binding,
protein kinase binding,
ubiquitin protein ligase binding,
transcription activator binding,
transcription activator activity,
RNA polymerase II transcription factor activity, enhancer binding,
promoter binding,
protein N-terminus binding,
phosphate binding,
NF-kappaB binding		 cytosol,
transcription factor complex		 transcription,
positive regulation of I-kappaB kinase/NF-kappaB cascade,
cytokine-mediated signaling pathway,
anti-apoptosis,
defense response to virus,
membrane protein intracellular domain proteolysis,
cellular defense response,
inflammatory response,
nucleotide-binding oligomerization domain containing 2 signaling pathway,
response to interleukin-1,
interspecies interaction between organisms,
positive regulation of NF-kappaB transcription factor activity,
positive regulation of transcription from RNA polymerase II promoter,
response to UV-B,
negative regulation of gene-specific transcription
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 254 VHRQVAIVFRTPPYADPSLQA - 14690596
LTP
1.00
 - IPT
0.42
 1MY7 4.11%
S 276 VRVSMQLRRPSDRELSEPMEF - 11931769
LTP
1.00
 - IPT
0.58
 1MY7 67.21%
S 276 VRVSMQLRRPSDRELSEPMEF RSK-5 12628924
LTP
1.00
 - IPT
0.58
 1MY7 67.21%
S 311 KRKRTYETFKSIMKKSPFSGP PKC_zeta 15210811
LTP
0.24
 - -
0.54
 1K3Z 36.89%
T 435 APKPTQAGEGTLSEALLQLQF MAPK1 15073167
LTP
0.33
 - -
0.75
 --
S 468 TDPAVFTDLASVDNSEFQQLL GSK-3_beta 15465828
LTP
0.91
 MOD_GSK3_1
 - -
0.53
 --
S 468 TDPAVFTDLASVDNSEFQQLL - 15280197
LTP
0.91
 MOD_GSK3_1
 - -
0.53
 --
T 505 EYPEAITRLVTGAQRPPDPAP - 15775976
LTP
0.48
 - -
0.75
 --
S 529 GAPGLPNGLLSGDEDFSSIAD CK2_group 10938077
LTP
0.55
 MOD_CK2_1
 - -
0.52
 --
S 529 GAPGLPNGLLSGDEDFSSIAD CK2_alpha 10938077
LTP
0.55
 MOD_CK2_1
 - -
0.52
 --
S 536 GLLSGDEDFSSIADMDFSALL IKK_group 10521409
LTP
0.93
 - -
0.35
 --
S 536 GLLSGDEDFSSIADMDFSALL IKK_beta 15128824
LTP
0.93
 - -
0.35
 --
S 536 GLLSGDEDFSSIADMDFSALL - 15849198
LTP
0.93
 - -
0.35
 --
S 536 GLLSGDEDFSSIADMDFSALL IKK_beta 15489227
LTP
0.93
 - -
0.35
 --
S 536 GLLSGDEDFSSIADMDFSALL IKK_alpha 15489227
LTP
0.93
 - -
0.35
 --
S 536 GLLSGDEDFSSIADMDFSALL IKK_epsilon 15489227
LTP
0.93
 - -
0.35
 --
S 536 GLLSGDEDFSSIADMDFSALL TBK1 15489227
LTP
0.93
 - -
0.35
 --
S 536 GLLSGDEDFSSIADMDFSALL - 15485852
LTP
0.93
 - -
0.35
 --
S 536 GLLSGDEDFSSIADMDFSALL - 12767944
LTP
0.93
 - -
0.35
 --

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