Substrate: FAK (Focal adhesion kinase)
Seq-ID: Q05397 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-17602   LYN_HUMAN
MINT-74938   BCAR1_HUMAN
MINT-3381308   SRC_HUMAN
MINT-6794892   PTN1_HUMAN
MINT-7294020   P53_HUMAN
MINT-7385708   SRC_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
SH2 domain binding,
signal transducer activity		 focal adhesion,
cytosol,
cytoskeleton		 signal complex assembly,
integrin-mediated signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 347 AENMADLIDGYCRLVNGTSQS - 12515828
LTP
1.00
 - -
0.21
 --
Y 397 HAVSVSETDDYAEIIDEEDTY FAK 7509446
LTP
1.00
 Fyn SH2;
GRB2 SH2;
GRB7 SH2;
NCK SH2;
PIK3R1 SH2;
Src SH2;
STAT3 SH2		 -
0.49
 --
Y 397 HAVSVSETDDYAEIIDEEDTY - 17192257
HTP
1.00
 Fyn SH2;
GRB2 SH2;
GRB7 SH2;
NCK SH2;
PIK3R1 SH2;
Src SH2;
STAT3 SH2		 -
0.49
 --
Y 397 HAVSVSETDDYAEIIDEEDTY - 18083107
HTP
1.00
 Fyn SH2;
GRB2 SH2;
GRB7 SH2;
NCK SH2;
PIK3R1 SH2;
Src SH2;
STAT3 SH2		 -
0.49
 --
Y 407 YAEIIDEEDTYTMPSTRDYEI - 7529876
LTP
1.00
 - -
0.50
 --
Y 407 YAEIIDEEDTYTMPSTRDYEI - 16254240
HTP
1.00
 - -
0.50
 --
Y 407 YAEIIDEEDTYTMPSTRDYEI - 15247219
LTP
1.00
 - -
0.50
 --
Y 407 YAEIIDEEDTYTMPSTRDYEI - 12960434
LTP
1.00
 - -
0.50
 --
Y 570 VKLGDFGLSRYMEDSTYYKAS - 18083107
HTP
1.00
 - TyrKc
0.09
 3BZ3 69.87%
Y 576 GLSRYMEDSTYYKASKGKLPI FAK 7529876
LTP
1.00
 - TyrKc
0.11
 2J0L 96.51%
Y 576 GLSRYMEDSTYYKASKGKLPI - 17192257
HTP
1.00
 - TyrKc
0.11
 2J0L 96.51%
Y 576 GLSRYMEDSTYYKASKGKLPI - 18083107
HTP
1.00
 - TyrKc
0.11
 2J0L 96.51%
Y 577 LSRYMEDSTYYKASKGKLPIK FAK 7529876
LTP
1.00
 - TyrKc
0.11
 2J0L 25.33%
Y 577 LSRYMEDSTYYKASKGKLPIK - 18083107
HTP
1.00
 - TyrKc
0.11
 2J0L 25.33%
S 722 PPKPSRPGYPSPRSSEGFYPS - 11160818
LTP
0.28
 - -
0.84
 --
S 722 PPKPSRPGYPSPRSSEGFYPS - 17192257
HTP
0.28
 - -
0.84
 --
S 732 SPRSSEGFYPSPQHMVQTNHY ROCK1 16760434
LTP
0.24
 - -
0.69
 --
S 840 ERFLKPDVRLSRGSIDREDGS - 11160818
LTP
1.00
 - -
0.65
 --
S 840 ERFLKPDVRLSRGSIDREDGS - 17081983
HTP
1.00
 - -
0.65
 --
S 840 ERFLKPDVRLSRGSIDREDGS - 17192257
HTP
1.00
 - -
0.65
 --
S 843 LKPDVRLSRGSIDREDGSLQG - 11160818
LTP
0.13
 - -
0.67
 --
S 843 LKPDVRLSRGSIDREDGSLQG - 17192257
HTP
0.13
 - -
0.67
 --
Y 861 LQGPIGNQHIYQPVGKPDPAA SRC 8941336
LTP
0.18
 - -
0.79
 --
Y 861 LQGPIGNQHIYQPVGKPDPAA SRC 11927607
LTP
0.18
 - -
0.79
 --
Y 861 LQGPIGNQHIYQPVGKPDPAA - 18083107
HTP
0.18
 - -
0.79
 --
S 892 PGHLGSLASLSSPADSYNEGV - 18669648
HTP
0.64
 - -
0.62
 --
S 910 EGVKLQPQEISPPPTANLDRS - 11160818
LTP
0.14
 - -
0.81
 1K04 77.87%
S 910 EGVKLQPQEISPPPTANLDRS - 17192257
HTP
0.14
 - -
0.81
 1K04 77.87%
S 910 EGVKLQPQEISPPPTANLDRS - 18669648
HTP
0.14
 - -
0.81
 1K04 77.87%
Y 925 ANLDRSNDKVYENVTGLVKAV - 12370821
LTP
1.00
 GRB2 SH2;
STAT3 SH2		 Focal_AT
0.45
 1K04 39.30%
Y 925 ANLDRSNDKVYENVTGLVKAV - 7997267
LTP
1.00
 GRB2 SH2;
STAT3 SH2		 Focal_AT
0.45
 1K04 39.30%

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