Substrate: BTK (Bruton's tyrosine kinase)
Seq-ID: Q06187 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-49799   IBTK_HUMAN
MINT-59463   BLNK_MOUSE
MINT-59465   BLNK_HUMAN
MINT-7230913   ARI3A_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphatidylinositol-3,4,5-trisphosphate binding,
identical protein binding,
metal ion binding,
non-membrane spanning protein tyrosine kinase activity,
ATP binding		 plasma membrane,
cytosol,
nucleus,
membrane raft		 induction of apoptosis by extracellular signals,
calcium-mediated signaling,
mesoderm development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 223 TSELKKVVALYDYMPMNANDL BTK 8630736
LTP
1.00
 - SH3
0.28
 --
Y 223 TSELKKVVALYDYMPMNANDL Abl 12445832
LTP
1.00
 - SH3
0.28
 --
Y 223 TSELKKVVALYDYMPMNANDL - 12573241
LTP
1.00
 - SH3
0.28
 --
Y 551 GLSRYVLDDEYTSSVGSKFPV Lyn 8630736
LTP
1.00
 - TyrKc
0.10
 1K2P 8.73%
Y 551 GLSRYVLDDEYTSSVGSKFPV BTK 8630736
LTP
1.00
 - TyrKc
0.10
 1K2P 8.73%
Y 551 GLSRYVLDDEYTSSVGSKFPV - 18083107
HTP
1.00
 - TyrKc
0.10
 1K2P 8.73%

Valid HTML 4.01 Transitional