Substrate: BAX (protein binding)
Seq-ID: Q07812 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-17572   1433S_HUMAN
MINT-7034069   B2L11_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein heterodimerization activity,
protein homodimerization activity,
lipid binding,
BH3 domain binding		 cytosol,
mitochondrial outer membrane,
endoplasmic reticulum membrane,
mitochondrial permeability transition pore complex		 B cell apoptosis,
induction of apoptosis by extracellular signals,
establishment or maintenance of transmembrane electrochemical gradient,
mitochondrial fragmentation involved in apoptosis,
positive regulation of neuron apoptosis,
regulation of protein homodimerization activity,
response to toxin,
activation of caspase activity by cytochrome c,
release of cytochrome c from mitochondria,
regulation of mitochondrial membrane potential,
nuclear fragmentation involved in apoptotic nuclear change,
negative regulation of survival gene product expression,
regulation of protein heterodimerization activity,
induction of apoptosis by intracellular signals,
cleavage of lamin,
induction of retinal programmed cell death,
protein homooligomerization,
DNA fragmentation involved in apoptotic nuclear change,
transformed cell apoptosis,
mitochondrial fusion,
release of matrix enzymes from mitochondria
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 184 TIFVAGVLTASLTIWKKMG   - 15642728
LTP
0.03
 - TRANS
0.01
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