Substrate: Runt-related transcription factor 2
Seq-ID: Q08775 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
specific transcriptional repressor activity,
chromatin binding,
ATP binding,
promoter binding,
sequence-specific DNA binding transcription factor activity,
protein binding		 cytoplasm,
transcription factor complex		 positive regulation of cell proliferation,
chondrocyte development,
transcription,
regulation of fibroblast growth factor receptor signaling pathway,
osteoblast fate commitment,
endochondral ossification,
cell maturation,
negative regulation of smoothened signaling pathway,
positive regulation of chondrocyte differentiation,
odontogenesis of dentine-containing tooth,
positive regulation of osteoblast differentiation,
regulation of odontogenesis of dentine-containing tooth,
positive regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 107 FWDPSTSRRFSPPSSSLQPGK - 12231506
LTP
1.00
 - -
0.71
 - medium
S 204 DHPAELVRTDSPNFLCSVLPS - 12231506
LTP
1.00
 - Runt
0.42
 - medium
S 551 QFPMVPGGDRSPSRMVPPCTT - 12231506
LTP
0.61
 - RunxI
0.70
 - medium
S 585 NQNDGVDADGSHSSSPTVLNS - 12231506
LTP
0.82
 - RunxI
0.85
 - medium
S 589 GVDADGSHSSSPTVLNSSGRM - 12231506
LTP
0.82
 - RunxI
0.82
 - medium

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