Substrate: Epidermal growth factor receptor kinase substrate 8 (Upon binding to EGF receptor enhances EGF-dependent mitogenic signals)
Seq-ID: Q12929 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-15664   ABI1_HUMAN
MINT-16848   US6NL_HUMAN
MINT-45897   ITB2_HUMAN
MINT-45900   ITB3_HUMAN
MINT-45901   ITB7_HUMAN
MINT-68090   HOOK2_HUMAN
MINT-7135462   SOS1_HUMAN
MINT-7214058   CD3E_HUMAN
MINT-7384705   BAIP2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3/SH2 adaptor activity epidermal growth factor receptor signaling pathway,
cell proliferation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 476 HQRKQEIKRLSTEHSSVSEYH - 18669648
HTP
0.27
 - -
0.56
 - medium
Y 525 PTSNRHIDRNYEPLKTQPKKY - 18083107
HTP
0.16
 - -
0.67
 - medium
S 659 KVPANITRQNSSSSDSGGSIV - 17081983
HTP
0.18
 - -
0.78
 - medium
S 659 KVPANITRQNSSSSDSGGSIV - 18669648
HTP
0.18
 - -
0.78
 - medium
S 662 ANITRQNSSSSDSGGSIVRDS - 18669648
HTP
0.24
 - -
0.81
 - medium
Y 774 RTVCPEGARVYSQITVQKAAL - 18083107
HTP
0.99
 - -
0.38
 - medium
S 811 QEKISAAASDSGVESFDEGSS - 17081983
HTP
0.29
 - -
0.58
 - medium
S 815 SAAASDSGVESFDEGSSH    - 17081983
HTP
0.26
 - -
0.60
 - medium

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