Substrate: Discs, large homolog 1 (Cell junction protein)
Seq-ID: Q12959 [Homo sapiens]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-48506   M3K3_HUMAN
MINT-68489   LCK_HUMAN
MINT-68490   KCNA3_HUMAN
MINT-72835   TOPK_HUMAN
MINT-73083   AT2B4_HUMAN
MINT-1901801   ADA17_HUMAN
MINT-7145813   ASAP1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein C-terminus binding,
potassium channel regulator activity,
protein kinase binding,
cytoskeletal protein binding,
phosphoprotein phosphatase activity,
phosphatase binding,
guanylate kinase activity		 sarcolemma,
cell-cell junction,
basolateral plasma membrane,
cytosol,
endoplasmic reticulum membrane,
postsynaptic membrane,
postsynaptic density		 cortical actin cytoskeleton organization,
mitotic cell cycle G1/S transition checkpoint,
endothelial cell proliferation,
establishment or maintenance of cell polarity,
actin filament organization,
interspecies interaction between organisms,
negative regulation of mitotic cell cycle,
cell-cell adhesion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 110 SLSPSVEKYRYQDEDTPPQEH - 18669648
HTP
0.86
 - MAGUK_N_PEST
0.74
 - low
T 115 VEKYRYQDEDTPPQEHISPQI - 18669648
HTP
0.39
 - MAGUK_N_PEST
0.75
 - low
S 122 DEDTPPQEHISPQITNEVIGP - 18669648
HTP
0.35
 - MAGUK_N_PEST
0.74
 - low
S 232 YEEITLERGNSGLGFSIAGGT CaM-KII_group 12933808
LTP
1.00
 - PDZ
0.41
 - low
S 567 IHDLREQMMNSSISSGSGSLR - 18669648
HTP
0.86
 - -
0.53
 - low
S 571 REQMMNSSISSGSGSLRTSQK - 18669648
HTP
1.00
 - -
0.58
 - low
S 575 MNSSISSGSGSLRTSQKRSLY - 18669648
HTP
0.94
 - -
0.48
 - low
S 619 FGDILHVINASDDEWWQARQV - 18220336
HTP
0.81
 - SH3
0.31
 - low
S 684 MGSKGLKHVTSNASDSESSYR - 15302935
HTP
0.55
 - -
0.68
 - low
S 684 MGSKGLKHVTSNASDSESSYR - 18669648
HTP
0.55
 - -
0.68
 - low
S 687 KGLKHVTSNASDSESSYRGQE - 15302935
HTP
0.55
 - -
0.63
 - low
S 687 KGLKHVTSNASDSESSYRGQE - 17081983
HTP
0.55
 - -
0.63
 - low
S 687 KGLKHVTSNASDSESSYRGQE - 18669648
HTP
0.55
 - -
0.63
 - low
Y 760 KRDYEVDGRDYHFVTSREQME - 18083107
HTP
0.92
 - GuKc
0.51
 - low

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