Substrate: Ser/thr-protein kinase 4 (Serine/threonine kinase)
Seq-ID: Q13043 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-6175057   AKT1_MOUSE
MINT-6175251   AKT1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
magnesium ion binding,
protein serine/threonine kinase activator activity,
protein serine/threonine kinase activity,
protein homodimerization activity,
ATP binding,
transcription factor binding		 cytoplasm,
nucleus		 cell morphogenesis,
apoptosis,
hippo signaling cascade,
negative regulation of canonical Wnt receptor signaling pathway,
positive regulation of apoptosis,
peptidyl-serine phosphorylation,
protein amino acid autophosphorylation,
intracellular protein kinase cascade
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 183 QLTDTMAKRNTVIGTPFWMAP MST1 11805089
LTP
1.00
 - S_TKc
0.25
 3COM 62.33%
S 320 REVDQDDEENSEEDEMDSGTM - 18669648
HTP
0.27
 - -
0.92
 --
Y 433 SDWKIPQDGDYEFLKSWTVED - 17192257
HTP
0.58
 - -
0.39
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