Substrate: eIF-2B (Translation initiation factor eIF-2B epsilon subunit (eIF-2B GDP-GTP exchange factor))
Seq-ID: Q13144 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
guanyl-nucleotide exchange factor activity,
translation initiation factor activity,
transferase activity,
translation initiation factor binding		 eukaryotic translation initiation factor 2B complex,
nucleus		 oligodendrocyte development,
myelination,
response to heat,
negative regulation of translational initiation in response to stress,
response to glucose stimulus,
astrocyte development,
response to peptide hormone stimulus,
ovarian follicle development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 466 AEEDEDDGEFSDDSGADQEKD - 11500362
LTP
0.05
 - -
0.91
 - medium
S 469 DEDDGEFSDDSGADQEKDKVK - 11500362
LTP
0.17
 - -
0.83
 - medium
S 535 SESESEQSMDSEEPDSRGGSP GSK-3_group 12133000
LTP
0.02
 - -
0.96
 - medium
S 544 DSEEPDSRGGSPQMDDIKVFQ - 15302935
HTP
0.28
 - -
0.74
 - medium
S 544 DSEEPDSRGGSPQMDDIKVFQ - 16097034
HTP
0.28
 - -
0.74
 - medium
S 544 DSEEPDSRGGSPQMDDIKVFQ - 17081983
HTP
0.28
 - -
0.74
 - medium
S 544 DSEEPDSRGGSPQMDDIKVFQ - 18088087
HTP
0.28
 - -
0.74
 - medium
S 544 DSEEPDSRGGSPQMDDIKVFQ - 18669648
HTP
0.28
 - -
0.74
 - medium
S 717 IQWLKEAEEESSEDD       - 11500362
LTP
0.35
 - W2
0.48
 - medium
S 717 IQWLKEAEEESSEDD       - 18669648
HTP
0.35
 - W2
0.48
 - medium
S 718 QWLKEAEEESSEDD        - 11500362
LTP
0.10
 - W2
0.55
 - medium
S 718 QWLKEAEEESSEDD        - 18669648
HTP
0.10
 - W2
0.55
 - medium

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