Substrate: DNA-repair protein XRCC4 (Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination)
Seq-ID: Q13426 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-51173   PNKP_HUMAN
MINT-51176   CSK21_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
DNA binding,
protein C-terminus binding		 cytosol,
DNA-dependent protein kinase-DNA ligase 4 complex,
DNA ligase IV complex		 double-strand break repair via nonhomologous end joining,
provirus integration,
positive regulation of ligase activity,
response to X-ray,
initiation of viral infection,
DNA ligation involved in DNA repair
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 193 VLNEKKTKIRSLHNKLLNAAQ - 14599745
LTP
1.00
 - COIL
0.38
 1IK9 38.52%
S 260 AVSKDDSIISSLDVTDIAPSR - 14599745
LTP
0.07
 - XRCC4
0.54
 --
S 304 QEKENSRPDSSLPETSKKEHI - 14599745
LTP
0.16
 - XRCC4
0.91
 --
S 315 LPETSKKEHISAENMSLETLR - 14599745
LTP
0.96
 - XRCC4
0.81
 --
S 320 KKEHISAENMSLETLRNSSPE - 14599745
LTP
1.00
 - XRCC4
0.80
 --
S 320 KKEHISAENMSLETLRNSSPE - 18669648
HTP
1.00
 - XRCC4
0.80
 --
T 323 HISAENMSLETLRNSSPEDLF - 14599745
LTP
1.00
 - XRCC4
0.77
 --
T 323 HISAENMSLETLRNSSPEDLF - 18669648
HTP
1.00
 - XRCC4
0.77
 --
S 327 ENMSLETLRNSSPEDLFDEI  - 14599745
LTP
1.00
 - XRCC4
0.73
 --
S 327 ENMSLETLRNSSPEDLFDEI  - 17081983
HTP
1.00
 - XRCC4
0.73
 --
S 327 ENMSLETLRNSSPEDLFDEI  - 18669648
HTP
1.00
 - XRCC4
0.73
 --
S 328 NMSLETLRNSSPEDLFDEI   - 14599745
LTP
0.08
 - XRCC4
0.71
 --
S 328 NMSLETLRNSSPEDLFDEI   - 17081983
HTP
0.08
 - XRCC4
0.71
 --
S 328 NMSLETLRNSSPEDLFDEI   - 18669648
HTP
0.08
 - XRCC4
0.71
 --

Valid HTML 4.01 Transitional