Substrate: IRF3 (Transcription factor)
Seq-ID: Q14653 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-6540731   CBP_HUMAN
MINT-6948128   TBK1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
RNA polymerase II transcription factor activity,
transcription cofactor activity,
sequence-specific DNA binding transcription factor activity		 cytosol,
nucleoplasm,
endosome membrane		 transcription from RNA polymerase II promoter,
I-kappaB kinase/NF-kappaB cascade,
interspecies interaction between organisms,
regulation of transcription, DNA-dependent,
response to virus
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 385 LVEMARVGGASSLENTVDLHI - 9463386
LTP
1.00
 - -
0.32
 1QWT 40.98%
S 385 LVEMARVGGASSLENTVDLHI - 14703513
LTP
1.00
 - -
0.32
 1QWT 40.98%
S 385 LVEMARVGGASSLENTVDLHI TBK1 17526488
LTP
1.00
 - -
0.32
 1QWT 40.98%
S 386 VEMARVGGASSLENTVDLHIS - 9463386
LTP
0.99
 - -
0.35
 1QWT 111.48%
S 386 VEMARVGGASSLENTVDLHIS IKK_epsilon 14703513
LTP
0.99
 - -
0.35
 1QWT 111.48%
S 386 VEMARVGGASSLENTVDLHIS TBK1 14703513
LTP
0.99
 - -
0.35
 1QWT 111.48%
S 386 VEMARVGGASSLENTVDLHIS TBK1 17526488
LTP
0.99
 - -
0.35
 1QWT 111.48%
S 396 SLENTVDLHISNSHPLSLTSD - 12524442
LTP
1.00
 - -
0.40
 1QWT 23.77%
S 396 SLENTVDLHISNSHPLSLTSD - 17526488
LTP
1.00
 - -
0.40
 1QWT 23.77%
S 398 ENTVDLHISNSHPLSLTSDQY - 9566918
LTP
0.31
 - -
0.36
 1QWT 40.16%
S 402 DLHISNSHPLSLTSDQYKAYL - 9566918
LTP
0.20
 - -
0.26
 1QWT 46.72%
T 404 HISNSHPLSLTSDQYKAYLQD - 9566918
LTP
0.16
 - -
0.25
 1QWT 35.62%
S 405 ISNSHPLSLTSDQYKAYLQDL - 9566918
LTP
0.09
 - -
0.26
 1QWT 33.61%
S 405 ISNSHPLSLTSDQYKAYLQDL - 17526488
LTP
0.09
 - -
0.26
 1QWT 33.61%

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