Substrate: Structural maintenance of chromosome 1-like 1 protein (Structural maintenance of chromosome 1-like 1 protein)
Seq-ID: Q14683 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14573   BRCA1_HUMAN
MINT-6492397   CTCF_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein heterodimerization activity,
microtubule motor activity,
chromatin binding,
ATP binding		 condensed nuclear chromosome,
condensed chromosome kinetochore,
cytoplasm,
cohesin core heterodimer		 cell division,
DNA repair,
negative regulation of DNA endoreduplication,
mitotic spindle organization,
mitotic sister chromatid cohesion,
response to radiation,
RNA splicing,
meiosis,
cell cycle checkpoint,
DNA damage response, signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 358 QEFEERMEEESQSQGRDLTLE - 17525332
HTP
0.32
 - COIL
0.70
 - medium
S 360 FEERMEEESQSQGRDLTLEEN - 15302935
HTP
0.09
 - COIL
0.71
 - medium
S 360 FEERMEEESQSQGRDLTLEEN - 17525332
HTP
0.09
 - COIL
0.71
 - medium
S 360 FEERMEEESQSQGRDLTLEEN - 18669648
HTP
0.09
 - COIL
0.71
 - medium
Y 600 GAKLVIDVIRYEPPHIKKALQ - 22067460
HTP
 - - SMC_hinge
0.19
 --
S 735 RHLALNLQEKSKLESELANFG - 22067460
HTP
 - - SMC_N
0.43
 --
S 951 PLSKGTMDDISQEEGSSQGED - 17525332
HTP
0.13
 - SMC_N
0.79
 - medium
S 956 TMDDISQEEGSSQGEDSVSGS - 22067460
HTP
 - - SMC_N
0.81
 --
S 957 MDDISQEEGSSQGEDSVSGSQ ATM 11877377
LTP
0.08
 MOD_PIKK_1
 - SMC_N
0.80
 - medium
S 957 MDDISQEEGSSQGEDSVSGSQ - 17525332
HTP
0.08
 MOD_PIKK_1
 - SMC_N
0.80
 - medium
S 957 MDDISQEEGSSQGEDSVSGSQ - 18669648
HTP
0.08
 MOD_PIKK_1
 - SMC_N
0.80
 - medium
S 957 MDDISQEEGSSQGEDSVSGSQ - 22067460
HTP
0.08
 MOD_PIKK_1
 - SMC_N
0.80
 - medium
S 962 QEEGSSQGEDSVSGSQRISSI - 15302935
HTP
0.15
 - SMC_N
0.70
 - medium
S 962 QEEGSSQGEDSVSGSQRISSI - 18669648
HTP
0.15
 - SMC_N
0.70
 - medium
S 964 EGSSQGEDSVSGSQRISSIYA - 18669648
HTP
0.25
 - SMC_N
0.64
 - medium
S 966 SSQGEDSVSGSQRISSIYARE ATM 11877377
LTP
0.28
 MOD_PIKK_1
 - SMC_N
0.57
 - medium
S 966 SSQGEDSVSGSQRISSIYARE - 17525332
HTP
0.28
 MOD_PIKK_1
 - SMC_N
0.57
 - medium
S 966 SSQGEDSVSGSQRISSIYARE - 18669648
HTP
0.28
 MOD_PIKK_1
 - SMC_N
0.57
 - medium
S 970 EDSVSGSQRISSIYAREALIE - 18669648
HTP
0.01
 - SMC_N
0.41
 - medium
S 970 EDSVSGSQRISSIYAREALIE - 22067460
HTP
0.01
 - SMC_N
0.41
 - medium
S 971 DSVSGSQRISSIYAREALIEI - 18669648
HTP
0.06
 - SMC_N
0.39
 - medium
Y 973 VSGSQRISSIYAREALIEIDY - 22067460
HTP
 - - SMC_N
0.34
 --
S 1033 PNMKAMEKLESVRDKFQETSD - 22067460
HTP
 - - COIL
0.56
 --

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