Substrate: Rho/Rac guanine nucleotide exchange factor 2 (Stimulates guanine nucleotide exchange of Rac and Rho)
Seq-ID: Q60875 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Rac guanyl-nucleotide exchange factor activity,
metal ion binding,
Rac GTPase binding,
microtubule binding		 neuronal cell body,
spindle,
dendritic shaft,
ruffle membrane,
Golgi apparatus,
microtubule,
tight junction		 cell division,
cell morphogenesis,
actin filament organization,
negative regulation of neurogenesis,
establishment of mitotic spindle orientation,
negative regulation of microtubule depolymerization,
mitosis,
positive regulation of NF-kappaB transcription factor activity,
regulation of Rho protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 163 TNIAGHFNDESPLGLRQILSQ - 19144319
HTP
0.33
 - -
0.38
 - low
S 174 PLGLRQILSQSTDSLNMRNRT - 19144319
HTP
1.00
 - -
0.43
 - low
S 646 ALPRGLFRLESFESLRGERLL - 17114649
HTP
1.00
 - -
0.28
 - low
S 646 ALPRGLFRLESFESLRGERLL - 19144319
HTP
1.00
 - -
0.28
 - low
S 781 ERWEKLSRANSRDGEAGRAAV - 19144319
HTP
1.00
 - -
0.62
 - low
T 795 EAGRAAVASVTPEKQATELAL - 19144319
HTP
0.00
 - -
0.58
 - low
S 885 ARRPLDPRRRSLPAGDALYLS - 19144319
HTP
0.08
 - -
0.62
 - low
S 931 FDDREAQELGSPEDRLQDSSD - 19144319
HTP
1.00
 - -
0.93
 - low
S 939 LGSPEDRLQDSSDPDTGSEEE - 19144319
HTP
0.03
 - -
0.96
 - low
S 940 GSPEDRLQDSSDPDTGSEEEV - 19144319
HTP
0.03
 - -
0.96
 - low
T 944 DRLQDSSDPDTGSEEEVSSRL - 19144319
HTP
0.03
 - -
0.94
 - low
S 955 GSEEEVSSRLSPPHSPRDFTR - 19144319
HTP
0.31
 - -
0.90
 - low
S 959 EVSSRLSPPHSPRDFTRMQDI - 17242355
HTP
0.12
 - -
0.89
 - low
S 959 EVSSRLSPPHSPRDFTRMQDI - 19144319
HTP
0.12
 - -
0.89
 - low

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