Substrate: Mitogen-activated protein kinase kinase kinase 1 (Ser/Thr protein kinase family. MAP kinase family)
Seq-ID: Q62925 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
MINT-5209624   GRAP1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
magnesium ion binding,
JUN kinase kinase kinase activity,
sphingolipid binding,
identical protein binding,
mitogen-activated protein kinase kinase binding,
mitogen-activated protein kinase binding,
JUN kinase binding,
ATP binding,
zinc ion binding,
MAP/ERK kinase kinase activity,
ubiquitin-protein ligase activity		 membrane fraction,
cytoplasm,
membrane		 response to osmotic stress,
positive regulation of gene-specific transcription from RNA polymerase II promoter,
positive regulation of viral transcription,
negative regulation of actin filament bundle assembly,
positive regulation of apoptosis,
protein oligomerization,
peptidyl-serine phosphorylation,
protein amino acid autophosphorylation,
protein ubiquitination involved in ubiquitin-dependent protein catabolic process,
activation of JNKK activity,
protein polyubiquitination
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 67 WRRQQLRKVRSVELDQLPEQP PAK1 12228228
LTP
0.95
 - -
0.78
 - low

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