Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Histone deacetylase 2 (Enzyme: Deacetylase)

Seq-ID:

Q92769 [Homo sapiens]

Download:

Interaction Network(s):

STRING

NetworKIN

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-73394   VE7_HPV16
MINT-73396   RB_HUMAN
MINT-4054286   MYBB_HUMAN
MINT-4544944   NPM_HUMAN
MINT-7302197   BUB1B_HUMAN
MINT-7761068   SRA1_HUMAN
MINT-7971268   DLG4_RAT

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, specific transcriptional repressor activity, transcription activator activity, histone deacetylase activity, enzyme binding, transcription factor binding	ESC/E(Z) complex, Sin3 complex, cytoplasm, NuRD complex	negative regulation of gene-specific transcription from RNA polymerase II promoter, positive regulation of cell proliferation, negative regulation of transcription factor activity, positive regulation of gene-specific transcription from RNA polymerase II promoter, positive regulation of proteolysis, transcription, histone deacetylation, positive regulation of receptor biosynthetic process, chromatin remodeling, negative regulation of MHC class II biosynthetic process, positive regulation of collagen biosynthetic process, maintenance of chromatin silencing, negative regulation of cell cycle

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	394	AIPEDAVHEDSGDEDGEDPDK	CK2_group	12082111	LTP	0.17	MOD_CK2_1	-	-	0.88	-	medium
S	394	AIPEDAVHEDSGDEDGEDPDK	CK2_alpha	12082111	LTP	0.17	MOD_CK2_1	-	-	0.88	-	medium
S	394	AIPEDAVHEDSGDEDGEDPDK	-	17081983	HTP	0.17	MOD_CK2_1	-	-	0.88	-	medium
S	394	AIPEDAVHEDSGDEDGEDPDK	-	18669648	HTP	0.17	MOD_CK2_1	-	-	0.88	-	medium
S	407	EDGEDPDKRISIRASDKRIAC	-	17287340	HTP	0.27		-	-	0.68	-	medium
S	407	EDGEDPDKRISIRASDKRIAC	-	18669648	HTP	0.27		-	-	0.68	-	medium
S	422	DKRIACDEEFSDSEDEGEGGR	CK2_group	12082111	LTP	0.33	MOD_CK2_1	-	-	0.75	-	medium
S	422	DKRIACDEEFSDSEDEGEGGR	-	17081983	HTP	0.33	MOD_CK2_1	-	-	0.75	-	medium
S	422	DKRIACDEEFSDSEDEGEGGR	-	17287340	HTP	0.33	MOD_CK2_1	-	-	0.75	-	medium
S	422	DKRIACDEEFSDSEDEGEGGR	-	18669648	HTP	0.33	MOD_CK2_1	-	-	0.75	-	medium
S	424	RIACDEEFSDSEDEGEGGRRN	CK2_group	12082111	LTP	0.40	MOD_CK2_1	-	-	0.76	-	medium
S	424	RIACDEEFSDSEDEGEGGRRN	-	17081983	HTP	0.40	MOD_CK2_1	-	-	0.76	-	medium
S	424	RIACDEEFSDSEDEGEGGRRN	-	17287340	HTP	0.40	MOD_CK2_1	-	-	0.76	-	medium
S	424	RIACDEEFSDSEDEGEGGRRN	-	18669648	HTP	0.40	MOD_CK2_1	-	-	0.76	-	medium