Substrate: MAP4K1 (Hematopoietic progenitor kinase)
Seq-ID: Q92918 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-7212968   GRB2_HUMAN
MINT-7244806   ABL1_HUMAN
MINT-7245502   SRC_HUMAN
MINT-7246558   FYN_HUMAN
MINT-7249558   NCK1_HUMAN
MINT-7252330   P85A_HUMAN
MINT-7252558   PLCG1_HUMAN
MINT-7254804   CRK_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
MAP kinase kinase kinase kinase activity,
small GTPase regulator activity,
ATP binding,
protein binding		 activation of JUN kinase activity,
activation of MAPKKK activity,
peptidyl-serine phosphorylation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 165 DFGISAQIGATLARRLSFIGT - 15743830
LTP
1.00
 - S_TKc
0.03
 - medium
S 171 QIGATLARRLSFIGTPYWMAP - 15743830
LTP
1.00
 - S_TKc
0.05
 - medium
S 366 ARLQPPRDLRSSSPRKQLSES - 15302935
HTP
0.95
 - -
0.93
 - medium
S 368 LQPPRDLRSSSPRKQLSESSD - 15302935
HTP
0.07
 - -
0.93
 - medium
S 374 LRSSSPRKQLSESSDDDYDDV - 17192257
HTP
0.33
 - -
0.89
 - medium
S 376 SSSPRKQLSESSDDDYDDVDI - 17192257
HTP
0.11
 - -
0.89
 - medium
Y 381 KQLSESSDDDYDDVDIPTPAE SYK 11514608
LTP
0.04
 BLNK SH2 -
0.91
 - medium
Y 381 KQLSESSDDDYDDVDIPTPAE - 11487585
LTP
0.04
 BLNK SH2 -
0.91
 - medium
Y 381 KQLSESSDDDYDDVDIPTPAE - 17192257
HTP
0.04
 BLNK SH2 -
0.91
 - medium
S 407 LPPKPKFRSPSDEGPGSMGDD - 17192257
HTP
1.00
 - -
0.94
 - medium
S 413 FRSPSDEGPGSMGDDGQLSPG - 17192257
HTP
0.09
 - -
0.92
 - medium
S 421 PGSMGDDGQLSPGVLVRCASG - 17192257
HTP
0.07
 - -
0.79
 - medium
S 586 TRAGNPIAHISPHRLLARKNM - 17192257
HTP
0.03
 - CNH
0.36
 - medium

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