Substrate: Alsin (Guanine nucleotide exchange factor)
Seq-ID: Q96Q42 [Homo sapiens]
Download:fasta csv
Interaction Network(s):
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-50977   1433B_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Ran guanyl-nucleotide exchange factor activity,
protein serine/threonine kinase activator activity,
Rac guanyl-nucleotide exchange factor activity,
protein homodimerization activity,
Rab GTPase binding,
Rab guanyl-nucleotide exchange factor activity		 centrosome,
early endosome,
cytosol,
lamellipodium,
protein complex,
ruffle		 positive regulation of protein kinase activity,
positive regulation of Rac GTPase activity,
regulation of endosome size,
endosome organization,
positive regulation of Rac protein signal transduction,
cell death
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 483 EETEGGSRRLSLPGLLSQVSP - 18669648
HTP
1.00
 - -
0.50
 - low
S 492 LSLPGLLSQVSPRLLRKAARV - 18669648
HTP
1.00
 - -
0.34
 - low
T 1344 DSPEILSRSQTQTLESLEFIP - 17525332
HTP
0.08
 - -
0.34
 - low
S 1464 CTGKSDSRSESPEPGYVVTSS - 18220336
HTP
0.28
 - -
0.44
 - low
S 1464 CTGKSDSRSESPEPGYVVTSS - 18669648
HTP
0.28
 - -
0.44
 - low

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