Substrate: Tyrosyl-DNA phosphodiesterase 1 (tyrosyl-DNA phosphodiesterase activity)
Seq-ID: Q9NUW8 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-7543535   ATM_HUMAN
MINT-7543877   XRCC1_HUMAN
MINT-7543888   H2AX_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
3`-tyrosyl-DNA phosphodiesterase activity,
exonuclease activity,
double-stranded DNA binding,
single-stranded DNA binding,
protein binding		 cytoplasm,
nucleus		 double-strand break repair,
single strand break repair,
cell death
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 11 MSQEGDYGRWTISSSDESEEE - 17081983
HTP
0.23
 - -
0.76
 - low
S 13 QEGDYGRWTISSSDESEEEKP - 17081983
HTP
0.23
 - -
0.78
 - low
S 14 EGDYGRWTISSSDESEEEKPK - 17081983
HTP
0.29
 - -
0.79
 - low
S 15 GDYGRWTISSSDESEEEKPKP - 17081983
HTP
0.25
 - -
0.80
 - low
S 61 AQKAAHKRKISPVKFSNTDSV - 18669648
HTP
0.24
 - -
0.65
 - low
S 90 GSQEDLGWCLSSSDDELQPEM - 17081983
HTP
1.00
 - -
0.66
 - low
S 91 SQEDLGWCLSSSDDELQPEMP - 17081983
HTP
0.11
 - -
0.66
 - low
S 92 QEDLGWCLSSSDDELQPEMPQ - 17081983
HTP
0.22
 - -
0.66
 - low
T 147 RLKEEEDEYETSGEGQDIWDM - 18669648
HTP
0.19
 - -
0.55
 - low
S 148 LKEEEDEYETSGEGQDIWDML - 18669648
HTP
0.02
 - -
0.56
 - low

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