Substrate: SREBP1 (Transcription factor)
Seq-ID: Q9WTN3 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sterol response element binding,
chromatin binding,
sequence-specific DNA binding transcription factor activity		 Golgi membrane,
ER to Golgi transport vesicle membrane,
integral to membrane,
endoplasmic reticulum membrane,
nucleus		 cellular response to starvation,
transcription,
positive regulation of transcription via sterol regulatory element binding,
positive regulation of triglyceride biosynthetic process,
positive regulation of histone deacetylation,
response to glucose stimulus,
negative regulation of insulin secretion,
insulin receptor signaling pathway,
cholesterol metabolic process,
negative regulation of transcription from RNA polymerase II promoter,
positive regulation of cholesterol biosynthetic process,
positive regulation of fatty acid biosynthetic process,
regulation of heart rate by chemical signal
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 108 PPSAPAALKMYPSVSPFSPGP - 17203969
HTP
0.15
 - -
0.58
 - low
S 112 PAALKMYPSVSPFSPGPGIKE - 17203969
HTP
0.90
 - -
0.55
 - low

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