Substrate: Gab2 (Adaptor molecule)
Seq-ID: Q9Z1S8 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphatidylinositol-3,4-bisphosphate binding,
phosphatidylinositol-3,4,5-trisphosphate binding,
transmembrane receptor protein tyrosine kinase adaptor protein activity		 plasma membrane,
cytoplasm		 positive regulation of cell proliferation,
cell migration,
integrin-mediated signaling pathway,
phosphoinositide-mediated signaling,
positive regulation of mast cell degranulation,
osteoclast differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 193 PTLSTSAPQEYLYLHQCISRR SRC_group 12819203
LTP
0.93
 SHC_group SH2 -
0.41
 - medium
S 402 MDNSRLHRASSCETYEYPARG - 17242355
HTP
0.17
 - -
0.66
 - medium
Y 441 RSNSASSDDNYVPMNPGSSTL - 9885561
LTP
1.00
 PIK3R1 SH2 -
0.79
 - medium
Y 441 RSNSASSDDNYVPMNPGSSTL - 11334882
LTP
1.00
 PIK3R1 SH2 -
0.79
 - medium
Y 465 ERPGDNSQSVYIPMSPGPHHF - 9885561
LTP
0.15
 PIK3R1 SH2 -
0.78
 - medium
Y 465 ERPGDNSQSVYIPMSPGPHHF - 11334882
LTP
0.15
 PIK3R1 SH2 -
0.78
 - medium
Y 573 STDSGDSEENYVPMQNPVSAS - 9885561
LTP
0.93
 PIK3R1 SH2 -
0.85
 - medium
Y 573 STDSGDSEENYVPMQNPVSAS - 11334882
LTP
0.93
 PIK3R1 SH2 -
0.85
 - medium
Y 603 APKKSTGSVDYLALDFQPGSP SRC_group 9885561
LTP
0.96
 PTPN11 SH2 -
0.70
 - medium
Y 632 SSVTSDEKVDYVQVDKEKTQA - 9885561
LTP
1.00
 PTPN11 SH2 -
0.71
 - medium
Y 632 SSVTSDEKVDYVQVDKEKTQA - 11640929
LTP
1.00
 PTPN11 SH2 -
0.71
 - medium

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