Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate: cdc25c (M-phase inducer phosphatase 3)

Seq-ID: P30307 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-16690 PLK1_HUMAN
MINT-3294433 1433Z_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

protein tyrosine phosphatase activity,
WW domain binding cytosol,
nucleoplasm regulation of cyclin-dependent protein kinase activity,
cell division,
traversing start control point of mitotic cell cycle,
protein amino acid dephosphorylation,
regulation of mitosis,
mitosis,
interspecies interaction between organisms,
DNA replication,
cell proliferation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 216 VSRSGLYRSPSMPENLNRPRL CHK2 10744722
LTP

0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 M-inducer_phosp
0.66
- low

S 216 VSRSGLYRSPSMPENLNRPRL - 15629715
LTP

0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 M-inducer_phosp
0.66
- low

S 216 VSRSGLYRSPSMPENLNRPRL CHK2 9836640
LTP

0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 M-inducer_phosp
0.66
- low

S 216 VSRSGLYRSPSMPENLNRPRL BRSK1 9543386
LTP

0.98
CDC25C 14-3-3;
NPHP1 14-3-3;
SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3 M-inducer_phosp
0.66
- low

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	216	VSRSGLYRSPSMPENLNRPRL	CHK2	10744722	LTP	0.98	CDC25C 14-3-3; NPHP1 14-3-3; SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	M-inducer_phosp	0.66	-	low
S	216	VSRSGLYRSPSMPENLNRPRL	-	15629715	LTP	0.98	CDC25C 14-3-3; NPHP1 14-3-3; SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	M-inducer_phosp	0.66	-	low
S	216	VSRSGLYRSPSMPENLNRPRL	CHK2	9836640	LTP	0.98	CDC25C 14-3-3; NPHP1 14-3-3; SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	M-inducer_phosp	0.66	-	low
S	216	VSRSGLYRSPSMPENLNRPRL	BRSK1	9543386	LTP	0.98	CDC25C 14-3-3; NPHP1 14-3-3; SFN 14-3-3; YWHAB 14-3-3; YWHAE 14-3-3; YWHAG 14-3-3; YWHAH 14-3-3; YWHAQ 14-3-3; YWHAZ 14-3-3	M-inducer_phosp	0.66	-	low