Substrate: TIE2 (TEK) (PTK receptor for angiopoietin 1)
Seq-ID: Q02763 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transmembrane receptor protein tyrosine kinase activity,
ATP binding,
protein binding		 basolateral plasma membrane,
integral to plasma membrane,
cell surface,
microvillus,
apical plasma membrane,
membrane raft		 positive regulation of ERK1 and ERK2 cascade,
protein amino acid phosphorylation,
protein oligomerization,
cell-cell signaling,
positive regulation of protein kinase B signaling cascade,
regulation of cell proliferation,
transmembrane receptor protein tyrosine kinase signaling pathway
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1108 ERKTYVNTTLYEKFTYAGIDC TIE2 10521483
LTP
0.08
 DOK_group PTB;
GRB14 SH2;
PIK3R1 SH2		 -
0.11
 1FVR 76.42%
Y 1108 ERKTYVNTTLYEKFTYAGIDC TIE2 12665569
LTP
0.08
 DOK_group PTB;
GRB14 SH2;
PIK3R1 SH2		 -
0.11
 1FVR 76.42%

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