List of substrates found:

Bcr  GH-R  IGF1-R  Insulin R  EPHB1  EPHB2 


Substrate: Bcr (Breakpoint cluster region protein)
Seq-ID: P11274 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 246 SESSCGVDGDYEDAELNPRFL Fes 8955135
LTP
1.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2
-
0.57
- medium
Y 276 GSRPPWPPLEYQPYQSIYVGG Fes 8955135
LTP
0.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.58
- medium
Y 279 PPWPPLEYQPYQSIYVGGMME Fes 8955135
LTP
1.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.58
- medium
Y 283 PLEYQPYQSIYVGGMMEGEGK Fes 8955135
LTP
1.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.61
- medium
Y 328 PRSFEDCGGGYTPDCSSNENL - 9467953
LTP
0.58
GRB10 SH2 -
0.56
- medium
Y 360 SSRVSPSPTTYRMFRDKSRSP Abl 9467953
LTP
0.53
GRB10 SH2 -
0.77
- medium
Y 436 ADGSFGTPPGYGCAADRAEEQ - 16497976
HTP
0.81
GRB10 SH2 -
0.71
- medium

Substrate: GH-R (Growth hormon receptor)
Seq-ID: P10912 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 487 NPSSLSNIDFYAQVSDITPAG JAK2 9121492
LTP
1.00
CISH SH2;
GRB10 SH2;
SOCS2 SH2;
STAT3 SH2;
STAT5 SH2
-
0.42
- low
Y 534 CQENFLMDNAYFCEADAKKCI - 9121492
LTP
0.93
GRB10 SH2;
STAT3 SH2;
STAT5 SH2
-
0.16
- low
Y 534 CQENFLMDNAYFCEADAKKCI - 8647880
LTP
0.93
GRB10 SH2;
STAT3 SH2;
STAT5 SH2
-
0.16
- low
Y 566 IQPSLNQEDIYITTESLTTAA - 9121492
LTP
1.00
GRB10 SH2;
STAT3 SH2;
STAT5 SH2
-
0.47
- low
Y 566 IQPSLNQEDIYITTESLTTAA - 8647880
LTP
1.00
GRB10 SH2;
STAT3 SH2;
STAT5 SH2
-
0.47
- low

Substrate: IGF1-R (Receptor tyrosine kinase)
Seq-ID: P08069 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1346 LRASFDERQPYAHMNGGRKNE IGF1R 8550552
LTP
1.00
Csk SH2;
GRB10 SH2;
PIK3R1 SH2;
PTPN11 SH2
-
0.63
--

Substrate: Insulin R (Receptor tyrosine kinase)
Seq-ID: P06213 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 999 GPLYASSNPEYLSASDVFPCS INSR 8662806
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS INSR 1658004
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS - 8393870
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS INSR 10340378
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 1185 IGDFGMTRDIYETDYYRKGGK INSR 7806540
LTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 100.87%
Y 1185 IGDFGMTRDIYETDYYRKGGK - 18083107
HTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 100.87%
Y 1189 GMTRDIYETDYYRKGGKGLLP INSR 7806540
LTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 67.69%
Y 1189 GMTRDIYETDYYRKGGKGLLP - 9506989
LTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 67.69%
Y 1189 GMTRDIYETDYYRKGGKGLLP - 18083107
HTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 67.69%
Y 1190 MTRDIYETDYYRKGGKGLLPV INSR 7806540
LTP
1.00
GRB10 SH2;
PTPN11 SH2;
SH2B1 SH2
TyrKc
0.17
1IR3 44.54%
Y 1190 MTRDIYETDYYRKGGKGLLPV - 9506989
LTP
1.00
GRB10 SH2;
PTPN11 SH2;
SH2B1 SH2
TyrKc
0.17
1IR3 44.54%
Y 1190 MTRDIYETDYYRKGGKGLLPV - 18083107
HTP
1.00
GRB10 SH2;
PTPN11 SH2;
SH2B1 SH2
TyrKc
0.17
1IR3 44.54%
Y 1355 GGSSLGFKRSYEEHIPYTHMN INSR 1321605
LTP
0.85
GRB10 SH2;
PIK3R1 SH2
-
0.50
--
Y 1361 FKRSYEEHIPYTHMNGGKKNG INSR 1321605
LTP
0.95
Csk SH2;
GRB10 SH2;
PIK3R1 SH2;
PTPN11 SH2;
SHC1 SH2
-
0.54
--

Substrate: EPHB1 (Receptor for member of the ephrinB family)
Seq-ID: Q07494 [Gallus gallus]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 928 DWLSAVKMSQYRDNFLSAGFT - 12223469
LTP
1.00
GRB10 SH2;
GRB7 SH2
SAM
0.15
- low
Y 928 DWLSAVKMSQYRDNFLSAGFT - 7731717
LTP
1.00
GRB10 SH2;
GRB7 SH2
SAM
0.15
- low

Substrate: EPHB2 (Receptor for member of the ephrinB family)
Seq-ID: P54763 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 938 EWLEAIKMGQYKESFANAGFT - 8798570
LTP
0.93
GRB10 SH2 SAM
0.17
--


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