List of substrates found:

Bcr  GH-R  IGF1-R  Insulin R  EPHB1  EPHB2 


Substrate: Bcr (Breakpoint cluster region protein)
Seq-ID: P11274 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
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Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 246 SESSCGVDGDYEDAELNPRFL Fes 8955135
LTP
1.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2
-
0.57
- medium
Y 276 GSRPPWPPLEYQPYQSIYVGG Fes 8955135
LTP
0.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.58
- medium
Y 279 PPWPPLEYQPYQSIYVGGMME Fes 8955135
LTP
1.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.58
- medium
Y 283 PLEYQPYQSIYVGGMMEGEGK Fes 8955135
LTP
1.00
ABL1 SH2;
GRB10 SH2;
GRB2 SH2;
SHC1 SH2;
SHC_group SH2
-
0.61
- medium
Y 328 PRSFEDCGGGYTPDCSSNENL - 9467953
LTP
0.58
GRB10 SH2 -
0.56
- medium
Y 360 SSRVSPSPTTYRMFRDKSRSP Abl 9467953
LTP
0.53
GRB10 SH2 -
0.77
- medium
Y 436 ADGSFGTPPGYGCAADRAEEQ - 16497976
HTP
0.81
GRB10 SH2 -
0.71
- medium

Substrate: GH-R (Growth hormon receptor)
Seq-ID: P10912 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 487 NPSSLSNIDFYAQVSDITPAG JAK2 9121492
LTP
1.00
CISH SH2;
GRB10 SH2;
SOCS2 SH2;
STAT3 SH2;
STAT5 SH2
-
0.42
- low
Y 534 CQENFLMDNAYFCEADAKKCI - 9121492
LTP
0.93
GRB10 SH2;
STAT3 SH2;
STAT5 SH2
-
0.16
- low
Y 534 CQENFLMDNAYFCEADAKKCI - 8647880
LTP
0.93
GRB10 SH2;
STAT3 SH2;
STAT5 SH2
-
0.16
- low
Y 566 IQPSLNQEDIYITTESLTTAA - 9121492
LTP
1.00
GRB10 SH2;
STAT3 SH2;
STAT5 SH2
-
0.47
- low
Y 566 IQPSLNQEDIYITTESLTTAA - 8647880
LTP
1.00
GRB10 SH2;
STAT3 SH2;
STAT5 SH2
-
0.47
- low

Substrate: IGF1-R (Receptor tyrosine kinase)
Seq-ID: P08069 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1346 LRASFDERQPYAHMNGGRKNE IGF1R 8550552
LTP
1.00
Csk SH2;
GRB10 SH2;
PIK3R1 SH2;
PTPN11 SH2
-
0.63
--

Substrate: Insulin R (Receptor tyrosine kinase)
Seq-ID: P06213 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 999 GPLYASSNPEYLSASDVFPCS INSR 8662806
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS INSR 1658004
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS - 8393870
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 999 GPLYASSNPEYLSASDVFPCS INSR 10340378
LTP
1.00
CRKL SH2;
GRB10 SH2;
IRS1 PTB;
IRS2 PTB;
RASA_group SH2;
SHC1 PTB;
SHC1 SH2;
STAT5 SH2
-
0.11
--
Y 1185 IGDFGMTRDIYETDYYRKGGK INSR 7806540
LTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 100.87%
Y 1185 IGDFGMTRDIYETDYYRKGGK - 18083107
HTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 100.87%
Y 1189 GMTRDIYETDYYRKGGKGLLP INSR 7806540
LTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 67.69%
Y 1189 GMTRDIYETDYYRKGGKGLLP - 9506989
LTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 67.69%
Y 1189 GMTRDIYETDYYRKGGKGLLP - 18083107
HTP
1.00
GRB10 SH2;
GRB14 SH2;
PTPN11 SH2;
SH2B1 SH2;
SH2B2 SH2
TyrKc
0.19
1IR3 67.69%
Y 1190 MTRDIYETDYYRKGGKGLLPV INSR 7806540
LTP
1.00
GRB10 SH2;
PTPN11 SH2;
SH2B1 SH2
TyrKc
0.17
1IR3 44.54%
Y 1190 MTRDIYETDYYRKGGKGLLPV - 9506989
LTP
1.00
GRB10 SH2;
PTPN11 SH2;
SH2B1 SH2
TyrKc
0.17
1IR3 44.54%
Y 1190 MTRDIYETDYYRKGGKGLLPV - 18083107
HTP
1.00
GRB10 SH2;
PTPN11 SH2;
SH2B1 SH2
TyrKc
0.17
1IR3 44.54%
Y 1355 GGSSLGFKRSYEEHIPYTHMN INSR 1321605
LTP
0.85
GRB10 SH2;
PIK3R1 SH2
-
0.50
--
Y 1361 FKRSYEEHIPYTHMNGGKKNG INSR 1321605
LTP
0.95
Csk SH2;
GRB10 SH2;
PIK3R1 SH2;
PTPN11 SH2;
SHC1 SH2
-
0.54
--

Substrate: EPHB1 (Receptor for member of the ephrinB family)
Seq-ID: Q07494 [Gallus gallus]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 928 DWLSAVKMSQYRDNFLSAGFT - 12223469
LTP
1.00
GRB10 SH2;
GRB7 SH2
SAM
0.15
- low
Y 928 DWLSAVKMSQYRDNFLSAGFT - 7731717
LTP
1.00
GRB10 SH2;
GRB7 SH2
SAM
0.15
- low

Substrate: EPHB2 (Receptor for member of the ephrinB family)
Seq-ID: P54763 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 938 EWLEAIKMGQYKESFANAGFT - 8798570
LTP
0.93
GRB10 SH2 SAM
0.17
--


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