List of substrates found:

IGF1-R  Tpo-R  IL-2R beta  PL scramblase 1 


Substrate: IGF1-R (Receptor tyrosine kinase)
Seq-ID: P08069 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 980 GVLYASVNPEYFSAADVYVPD IGF1R 8550552
LTP
1.00
CRK SH2;
IRS1 PTB;
RASA_group SH2;
SHC PTB
-
0.07
1P4O 89.96%
Y 980 GVLYASVNPEYFSAADVYVPD IGF1R 8940173
LTP
1.00
CRK SH2;
IRS1 PTB;
RASA_group SH2;
SHC PTB
-
0.07
1P4O 89.96%
Y 980 GVLYASVNPEYFSAADVYVPD - 7537849
LTP
1.00
CRK SH2;
IRS1 PTB;
RASA_group SH2;
SHC PTB
-
0.07
1P4O 89.96%
Y 980 GVLYASVNPEYFSAADVYVPD - 7559478
LTP
1.00
CRK SH2;
IRS1 PTB;
RASA_group SH2;
SHC PTB
-
0.07
1P4O 89.96%

Substrate: Tpo-R (Thrombopoietin R mlp belongs to the hematopoietic R superfamily)
Seq-ID: P40238 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cytokine receptor activity integral to plasma membrane cell proliferation
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
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Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 626 CCTTHIANHSYLPLSYWQQP  - 9122198
LTP
1.00
SHC1 SH2;
SHC PTB;
STAT5 SH2
-
0.18
- medium

Substrate: IL-2R beta (Cytokin receptor)
Seq-ID: P14784 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 364 SLTSCFTNQGYFFFHLPDALE - 7499411
LTP
1.00
SHC PTB -
0.13
- medium
Y 364 SLTSCFTNQGYFFFHLPDALE - 8643566
LTP
1.00
SHC PTB -
0.13
- medium

Substrate: PL scramblase 1 (Erythrocytes phospholipid scramblase)
Seq-ID: O15162 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 69 AGFPVPNQPVYNQPVYNQPVG Abl 11390389
LTP
0.34
SHC PTB -
0.51
- low
Y 69 AGFPVPNQPVYNQPVYNQPVG SRC 12871937
LTP
0.34
SHC PTB -
0.51
- low
Y 74 PNQPVYNQPVYNQPVGAAGVP Abl 11390389
LTP
0.45
SHC PTB -
0.45
- low
Y 74 PNQPVYNQPVYNQPVGAAGVP SRC 12871937
LTP
0.45
SHC PTB -
0.45
- low


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