a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

IGF1-R  Tpo-R  IL-2R beta  PL scramblase 1 

Substrate:	IGF1-R (Receptor tyrosine kinase)
Seq-ID:	P08069 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-15644   GRB10_HUMAN MINT-18053   IRS2_HUMAN MINT-1774754   ARHGC_MOUSE MINT-1774976   ARHGC_HUMAN MINT-6800783   PTN1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process phosphoinositide 3-kinase binding, identical protein binding, insulin-like growth factor receptor activity, insulin binding, metal ion binding, insulin receptor binding, insulin receptor substrate binding, ATP binding, insulin-like growth factor I binding microsome, integral to plasma membrane positive regulation of DNA replication, positive regulation of cell proliferation, positive regulation of cell migration, anti-apoptosis, phosphoinositide 3-kinase cascade, phosphoinositide-mediated signaling, immune response, protein amino acid autophosphorylation, insulin receptor signaling pathway, protein tetramerization
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	980	GVLYASVNPEYFSAADVYVPD	IGF1R	8550552	LTP	1.00		CRK SH2; IRS1 PTB; RASA_group SH2; SHC PTB	-	0.07	1P4O	89.96%
Y	980	GVLYASVNPEYFSAADVYVPD	IGF1R	8940173	LTP	1.00		CRK SH2; IRS1 PTB; RASA_group SH2; SHC PTB	-	0.07	1P4O	89.96%
Y	980	GVLYASVNPEYFSAADVYVPD	-	7537849	LTP	1.00		CRK SH2; IRS1 PTB; RASA_group SH2; SHC PTB	-	0.07	1P4O	89.96%
Y	980	GVLYASVNPEYFSAADVYVPD	-	7559478	LTP	1.00		CRK SH2; IRS1 PTB; RASA_group SH2; SHC PTB	-	0.07	1P4O	89.96%

Substrate:	Tpo-R (Thrombopoietin R mlp belongs to the hematopoietic R superfamily)
Seq-ID:	P40238 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process cytokine receptor activity integral to plasma membrane cell proliferation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	626	CCTTHIANHSYLPLSYWQQP	-	9122198	LTP	1.00		SHC1 SH2; SHC PTB; STAT5 SH2	-	0.18	-	medium

Substrate:	IL-2R beta (Cytokin receptor)
Seq-ID:	P14784 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process interleukin-2 receptor activity external side of plasma membrane, integral to plasma membrane protein complex assembly, positive regulation of survival gene product expression, interspecies interaction between organisms
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	364	SLTSCFTNQGYFFFHLPDALE	-	7499411	LTP	1.00		SHC PTB	-	0.13	-	medium
Y	364	SLTSCFTNQGYFFFHLPDALE	-	8643566	LTP	1.00		SHC PTB	-	0.13	-	medium

Substrate:	PL scramblase 1 (Erythrocytes phospholipid scramblase)
Seq-ID:	O15162 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-66053   CPSF6_HUMAN MINT-66152   CRY1_HUMAN MINT-66176   DTX2_HUMAN MINT-66313   LASP1_HUMAN MINT-66701   GNAI2_HUMAN MINT-66739   K1683_HUMAN MINT-66992   HXB6_HUMAN MINT-67029   MED15_HUMAN MINT-67190   NECP2_HUMAN MINT-67221   F103A_HUMAN MINT-67237   PLS4_HUMAN MINT-67637   VASP_HUMAN MINT-67716   BORG5_HUMAN MINT-67916   TFG_HUMAN MINT-67975   ILF3_HUMAN MINT-68323   ZN638_HUMAN MINT-2861816   ATN1_HUMAN MINT-2861835   RERE_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process SH3 domain binding, calcium ion binding, phospholipid scramblase activity plasma membrane, integral to membrane phospholipid scrambling, platelet activation, response to virus
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	69	AGFPVPNQPVYNQPVYNQPVG	Abl	11390389	LTP	0.34		SHC PTB	-	0.51	-	low
Y	69	AGFPVPNQPVYNQPVYNQPVG	SRC	12871937	LTP	0.34		SHC PTB	-	0.51	-	low
Y	74	PNQPVYNQPVYNQPVGAAGVP	Abl	11390389	LTP	0.45		SHC PTB	-	0.45	-	low
Y	74	PNQPVYNQPVYNQPVGAAGVP	SRC	12871937	LTP	0.45		SHC PTB	-	0.45	-	low