a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	JAK2 (Cytoplasmic tyrosine kinase)
Seq-ID:	O60674 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-13705   BRCA1_HUMAN MINT-61281   G3BP1_HUMAN MINT-74562   EGFR_HUMAN MINT-74563   ERBB3_HUMAN MINT-6764602   PTN1_HUMAN MINT-7250518   NCK1_HUMAN MINT-7251766   P85A_HUMAN MINT-7252666   PLCG1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process histone binding, Janus kinase activity, histone kinase activity (H3-Y41 specific), non-membrane spanning protein tyrosine kinase activity, ATP binding, growth hormone receptor binding, SH2 domain binding cytoskeleton, endomembrane system activation of JAK2 kinase activity, cytokine-mediated signaling pathway, cellular component movement, mesoderm development, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, erythrocyte differentiation, protein amino acid autophosphorylation, JAK-STAT cascade involved in growth hormone signaling pathway, response to antibiotic
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1007	LTKVLPQDKEYYKVKEPGESP	JAK2	9111318	LTP	1.00		SOCS1 SH2; SOCS3 SH2	TyrKc	0.27	3E62	61.14%