a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	INF-alpha REC (Interferon receptor)
Seq-ID:	P17181 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	MINT-73134   TYK2_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process type I interferon receptor activity integral to plasma membrane blood coagulation, JAK-STAT cascade, response to virus
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	466	AAKVFLRCINYVFFPSLKPSS	Tyk2	8605876	LTP	1.00		STAT1 SH2; STAT2 SH2; STAT3 SH2; TYK2 SH2	-	0.03	-	low
Y	466	AAKVFLRCINYVFFPSLKPSS	Tyk2	8700538	LTP	1.00		STAT1 SH2; STAT2 SH2; STAT3 SH2; TYK2 SH2	-	0.03	-	low
Y	481	SLKPSSSIDEYFSEQPLKNLL	Tyk2	7526154	LTP	1.00		STAT2 SH2; TYK2 SH2	-	0.24	-	low

Substrate:	STAT 1 (Transcription factor)
Seq-ID:	P42224 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-74755   ERBB2_HUMAN MINT-7264037   CBP_MOUSE
GO-Terms:	[show] Molecular Function Cellular Component Biological Process calcium ion binding, hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity, sequence-specific DNA binding transcription factor activity, protein binding cytoplasm, nucleolus transcription from RNA polymerase II promoter, activation of caspase activity, I-kappaB kinase/NF-kappaB cascade, interspecies interaction between organisms, regulation of transcription, DNA-dependent, response to virus, tyrosine phosphorylation of STAT protein
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	701	MELDGPKGTGYIKTELISVSE	-	7592750	LTP	1.00		STAT1 SH2; STAT2 SH2	-	0.47	1BF5	139.74%
Y	701	MELDGPKGTGYIKTELISVSE	-	15322115	LTP	1.00		STAT1 SH2; STAT2 SH2	-	0.47	1BF5	139.74%
Y	701	MELDGPKGTGYIKTELISVSE	JAK2	11438544	LTP	1.00		STAT1 SH2; STAT2 SH2	-	0.47	1BF5	139.74%
Y	701	MELDGPKGTGYIKTELISVSE	JAK1	11438544	LTP	1.00		STAT1 SH2; STAT2 SH2	-	0.47	1BF5	139.74%
Y	701	MELDGPKGTGYIKTELISVSE	-	10748192	LTP	1.00		STAT1 SH2; STAT2 SH2	-	0.47	1BF5	139.74%
Y	701	MELDGPKGTGYIKTELISVSE	SRC	14978237	LTP	1.00		STAT1 SH2; STAT2 SH2	-	0.47	1BF5	139.74%
Y	701	MELDGPKGTGYIKTELISVSE	JAK2	14978237	LTP	1.00		STAT1 SH2; STAT2 SH2	-	0.47	1BF5	139.74%
Y	701	MELDGPKGTGYIKTELISVSE	JAK1	14978237	LTP	1.00		STAT1 SH2; STAT2 SH2	-	0.47	1BF5	139.74%

Substrate:	STAT 2 (Transcription factor)
Seq-ID:	P52630 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	MINT-7264052   CBP_MOUSE
GO-Terms:	[show] Molecular Function Cellular Component Biological Process calcium ion binding, hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity, sequence-specific DNA binding transcription factor activity, protein binding cytoplasm, nucleus transcription, regulation of transcription from RNA polymerase II promoter, JAK-STAT cascade, interspecies interaction between organisms, response to virus
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	690	EKVNLQERRKYLKHRLIVVSN	JAK_group	7532278	LTP	1.00		STAT1 SH2; STAT2 SH2	-	0.19	-	medium