a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

FCER1G  CD3 gamma  CD3 epsilon  CD3 zeta  CD3 delta 

Substrate:	FCER1G (FceRI gamma)
Seq-ID:	P30273 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process IgE binding, transmembrane receptor activity integral to plasma membrane cell surface receptor linked signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	65	ITSYEKSDGVYTGLSTRNQET	-	18088087	HTP	1.00		FES SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.29	-	low
Y	65	ITSYEKSDGVYTGLSTRNQET	-	18083107	HTP	1.00		FES SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.29	-	low
Y	76	TGLSTRNQETYETLKHEKPPQ	-	18088087	HTP	1.00		FES SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.54	-	low
Y	76	TGLSTRNQETYETLKHEKPPQ	-	18083107	HTP	1.00		FES SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.54	-	low

Substrate:	CD3 gamma (T-cell surface glycoprotein CD3 gamma chain (T3 gamma chain) (from PhosphoBase))
Seq-ID:	P09693 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process T cell receptor binding, protein heterodimerization activity, receptor signaling complex scaffold activity, transmembrane receptor activity integral to plasma membrane protein complex assembly, T cell activation, protein transport, establishment or maintenance of cell polarity, regulation of apoptosis, cell surface receptor linked signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	160	KQTLLPNDQLYQPLKDREDDQ	-	16094384	HTP	0.95		Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.48	-	low
Y	171	QPLKDREDDQYSHLQGNQLRR	-	16094384	HTP	1.00		SYK SH2; ZAP70 SH2	ITAM	0.54	-	low

Substrate:	CD3 epsilon (T cell surface glycoprotein)
Seq-ID:	P07766 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-7213943   NCK2_HUMAN MINT-7214058   EPS8_HUMAN MINT-7214076   ES8L2_HUMAN MINT-7214253   ES8L1_HUMAN MINT-7234008   NCK1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process SH3 domain binding, T cell receptor binding, protein heterodimerization activity, protein kinase binding, receptor signaling complex scaffold activity, transmembrane receptor activity, receptor signaling protein activity external side of plasma membrane, integral to plasma membrane signal complex assembly, G-protein coupled receptor protein signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	188	ERPPPVPNPDYEPIRKGQRDL	-	15592455	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.67	-	medium
Y	188	ERPPPVPNPDYEPIRKGQRDL	-	16094384	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.67	-	medium
Y	188	ERPPPVPNPDYEPIRKGQRDL	-	15659558	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.67	-	medium
Y	199	EPIRKGQRDLYSGLNQRRI	-	12522270	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.40	-	medium
Y	199	EPIRKGQRDLYSGLNQRRI	-	15144186	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.40	-	medium
Y	199	EPIRKGQRDLYSGLNQRRI	-	15592455	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.40	-	medium
Y	199	EPIRKGQRDLYSGLNQRRI	-	16094384	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.40	-	medium
Y	199	EPIRKGQRDLYSGLNQRRI	-	15659558	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.40	-	medium
Y	199	EPIRKGQRDLYSGLNQRRI	-	18083107	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.40	-	medium

Substrate:	CD3 zeta (T-cell surface glycoprotein CD3 zeta chain precursor (from PhosphoBase))
Seq-ID:	P20963 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-60782   LCK_HUMAN MINT-7301967   NCK1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein homodimerization activity, transmembrane receptor activity cytoplasm, integral to membrane interspecies interaction between organisms
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	72	PAYQQGQNQLYNELNLGRREE	-	15144186	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.44	-	medium
Y	72	PAYQQGQNQLYNELNLGRREE	-	15592455	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.44	-	medium
Y	72	PAYQQGQNQLYNELNLGRREE	-	16094384	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.44	-	medium
Y	72	PAYQQGQNQLYNELNLGRREE	-	15659558	HTP	1.00		Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.44	-	medium
Y	83	NELNLGRREEYDVLDKRRGRD	-	12522270	HTP	1.00		Fyn SH2; Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.47	-	medium
Y	83	NELNLGRREEYDVLDKRRGRD	-	15592455	HTP	1.00		Fyn SH2; Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.47	-	medium
Y	83	NELNLGRREEYDVLDKRRGRD	-	16094384	HTP	1.00		Fyn SH2; Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.47	-	medium
Y	83	NELNLGRREEYDVLDKRRGRD	-	15659558	HTP	1.00		Fyn SH2; Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.47	-	medium
Y	111	QRRKNPQEGLYNELQKDKMAE	Fyn	8578591	LTP	1.00	LIG_TYR_ITAM	Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.63	-	medium
Y	111	QRRKNPQEGLYNELQKDKMAE	-	12522270	HTP	1.00	LIG_TYR_ITAM	Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.63	-	medium
Y	111	QRRKNPQEGLYNELQKDKMAE	-	15144186	HTP	1.00	LIG_TYR_ITAM	Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.63	-	medium
Y	111	QRRKNPQEGLYNELQKDKMAE	-	15592455	HTP	1.00	LIG_TYR_ITAM	Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.63	-	medium
Y	111	QRRKNPQEGLYNELQKDKMAE	-	16094384	HTP	1.00	LIG_TYR_ITAM	Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.63	-	medium
Y	111	QRRKNPQEGLYNELQKDKMAE	-	15659558	HTP	1.00	LIG_TYR_ITAM	Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.63	-	medium
Y	111	QRRKNPQEGLYNELQKDKMAE	-	18083107	HTP	1.00	LIG_TYR_ITAM	Fyn SH2; Lck SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.63	-	medium
Y	123	ELQKDKMAEAYSEIGMKGERR	Fyn	8578591	LTP	1.00	LIG_TYR_ITAM	Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.49	-	medium
Y	123	ELQKDKMAEAYSEIGMKGERR	-	12522270	HTP	1.00	LIG_TYR_ITAM	Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.49	-	medium
Y	123	ELQKDKMAEAYSEIGMKGERR	-	16094384	HTP	1.00	LIG_TYR_ITAM	Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.49	-	medium
Y	123	ELQKDKMAEAYSEIGMKGERR	-	15659558	HTP	1.00	LIG_TYR_ITAM	Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.49	-	medium
Y	142	RRRGKGHDGLYQGLSTATKDT	-	12522270	HTP	1.00		Fyn SH2; Lck SH2; PLCG1 SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.65	-	medium
Y	142	RRRGKGHDGLYQGLSTATKDT	-	15592455	HTP	1.00		Fyn SH2; Lck SH2; PLCG1 SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.65	-	medium
Y	142	RRRGKGHDGLYQGLSTATKDT	-	16094384	HTP	1.00		Fyn SH2; Lck SH2; PLCG1 SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.65	-	medium
Y	142	RRRGKGHDGLYQGLSTATKDT	-	15659558	HTP	1.00		Fyn SH2; Lck SH2; PLCG1 SH2; SHC1 SH2; SYK SH2; ZAP70 SH2	ITAM	0.65	-	medium
Y	153	QGLSTATKDTYDALHMQALPP	-	16094384	HTP	0.90		Fyn SH2; Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.65	-	medium
Y	153	QGLSTATKDTYDALHMQALPP	-	15659558	HTP	0.90		Fyn SH2; Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.65	-	medium

Substrate:	CD3 delta (T cell surface glycoprotein)
Seq-ID:	P04234 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	MINT-3374054   GCR_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein heterodimerization activity, transmembrane receptor activity cytoplasm, integral to membrane positive thymic T cell selection, cell surface receptor linked signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	149	TQALLRNDQVYQPLRDRDDAQ	-	12522270	HTP	1.00		Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.36	-	low
Y	149	TQALLRNDQVYQPLRDRDDAQ	-	15144186	HTP	1.00		Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.36	-	low
Y	149	TQALLRNDQVYQPLRDRDDAQ	-	15592455	HTP	1.00		Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.36	-	low
Y	149	TQALLRNDQVYQPLRDRDDAQ	-	16094384	HTP	1.00		Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.36	-	low
Y	149	TQALLRNDQVYQPLRDRDDAQ	-	15659558	HTP	1.00		Lck SH2; SYK SH2; ZAP70 SH2	ITAM	0.36	-	low
Y	160	QPLRDRDDAQYSHLGGNWARN	-	12522270	HTP	1.00		SYK SH2; ZAP70 SH2	ITAM	0.38	-	low
Y	160	QPLRDRDDAQYSHLGGNWARN	-	15592455	HTP	1.00		SYK SH2; ZAP70 SH2	ITAM	0.38	-	low
Y	160	QPLRDRDDAQYSHLGGNWARN	-	16094384	HTP	1.00		SYK SH2; ZAP70 SH2	ITAM	0.38	-	low
Y	160	QPLRDRDDAQYSHLGGNWARN	-	15659558	HTP	1.00		SYK SH2; ZAP70 SH2	ITAM	0.38	-	low