Click on substrate name for additional information.


Substrate: C/EBP alpha (Transcription factor)
Seq-ID: P53566 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
MINT-5225582   FOXO1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein homodimerization activity,
specific RNA polymerase II transcription factor activity,
RNA polymerase II transcription factor activity, enhancer binding,
transcription factor binding,
promoter binding		 positive regulation of gene-specific transcription from RNA polymerase II promoter,
lung development,
macrophage differentiation,
transcription,
cytokine-mediated signaling pathway,
negative regulation of cell proliferation,
white fat cell differentiation,
cellular response to organic cyclic substance,
urea cycle,
embryonic placenta development,
cell maturation,
brown fat cell differentiation,
liver development,
positive regulation of fat cell differentiation,
cellular response to lithium ion,
negative regulation of transcription from RNA polymerase II promoter,
mitochondrion organization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 193 PPPPPPHPHASPAHLAAPHLQ CDK6 16537903
LTP
0.56
 - -
0.92
 - low

Substrate: Retinoblastoma like 2 (Cell cycle control protein)
Seq-ID: Q08999 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-16160   RBBP8_HUMAN
MINT-68815   VE7_HPV16
MINT-6665139   E1A_ADE05
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
DNA binding,
protein binding		 chromatin modification,
transcription,
regulation of transcription,
cell cycle,
regulation of lipid kinase activity
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 401 FDKSKALRISTPLTGVRYIKE CDK6 11157749
LTP
1.00
 - -
0.31
 - medium
S 672 SPTTLYDRYSSPPASTTRRRL CDK6 11157749
LTP
1.00
 - -
0.61
 - medium
S 1035 SQANMDAPPLSPYPFVRTGSP CDK6 11157749
LTP
1.00
 - -
0.68
 - medium

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