List of substrates found:


Substrate: APC (Adhesion molecule)
Seq-ID: P25054 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-1780719   DLG4_MOUSE
MINT-3296068   1433Z_HUMAN
MINT-3975353   1433S_HUMAN
MINT-4508229   CTNB1_HUMAN
MINT-6732416   SCRIB_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
microtubule plus-end binding,
protein kinase regulator activity,
protein kinase binding,
beta-catenin binding,
gamma-catenin binding		 centrosome,
Axin-APC-beta-catenin-GSK3B complex,
beta-catenin destruction complex,
cytosol,
lateral plasma membrane,
kinetochore,
adherens junction,
nucleus,
tight junction		 negative regulation of cyclin-dependent protein kinase activity,
positive regulation of protein catabolic process,
protein complex assembly,
positive regulation of cell migration,
positive regulation of pseudopodium assembly,
cell cycle arrest,
cytokinesis after mitosis,
negative regulation of canonical Wnt receptor signaling pathway,
positive regulation of apoptosis,
canonical Wnt receptor signaling pathway,
negative regulation of microtubule depolymerization,
regulation of attachment of spindle microtubules to kinetochore,
response to DNA damage stimulus,
cell adhesion,
tight junction assembly,
mitotic cell cycle spindle assembly checkpoint
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 1279 ICFSRCSSLSSLSSAEDEIGC CK1_epsilon 11487578
LTP
1.00
 MOD_CK1_1
 - APC_crr
0.37
 - medium
S 1392 LMFSRCTSVSSLDSFESRSIA CK1_epsilon 11487578
LTP
1.00
 MOD_CK1_1
 - APC_crr
0.48
 - medium

Substrate: Casein kinase I, epsilon (Casein kinase I, epsilon isoform)
Seq-ID: P49674 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-67492   DVL2_HUMAN
MINT-1892205   OCLN_HUMAN
MINT-7264275   1433F_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
ATP binding,
protein binding		 cytosol,
nucleus		 protein amino acid phosphorylation,
DNA repair,
signal transduction,
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 323 REERMGQLRGSATRALPPGPP CK1_epsilon 10542239
LTP
0.08
 - -
0.83
 - medium
T 325 ERMGQLRGSATRALPPGPPTG CK1_epsilon 10542239
LTP
0.09
 - -
0.83
 - medium
T 334 ATRALPPGPPTGATANRLRSA CK1_epsilon 10542239
LTP
0.00
 - -
0.79
 - medium
T 337 ALPPGPPTGATANRLRSAAEP CK1_epsilon 10542239
LTP
0.05
 - -
0.79
 - medium
S 368 PAGNTSPRAISRVDRERKVSM CK1_epsilon 10542239
LTP
0.42
 - -
0.73
 - medium
S 405 GRQEVSRIPASQTSVPFDHLG CK1_epsilon 10542239
LTP
0.18
 MOD_CK1_1
 - -
0.78
 - medium
T 407 QEVSRIPASQTSVPFDHLGK  CK1_epsilon 10542239
LTP
0.00
 MOD_CK1_1
 - -
0.77
 - medium
S 408 EVSRIPASQTSVPFDHLGK   CK1_epsilon 10542239
LTP
0.07
 MOD_CK1_1
 - -
0.77
 - medium

Substrate: PER1 (protein binding)
Seq-ID: O35973 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
signal transducer activity,
protein binding		 cytoplasm,
nucleus		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
transcription,
circadian rhythm,
response to light stimulus
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 661 CASSSSYTASSASDDDKQRAG CK1_epsilon 15148313
LTP
1.00
 MOD_CK1_1
 - -
0.71
 - medium
S 663 SSSSYTASSASDDDKQRAGPV CK1_epsilon 15148313
LTP
1.00
 MOD_CK1_1
 - -
0.73
 - medium
S 714 SPLALANKAESVVSVTSQCSF CK1_epsilon 16750171
LTP
1.00
 MOD_CK1_1
 - -
0.35
 - medium

Substrate: Period circadian protein 2 (Transcription regulatory protein)
Seq-ID: O15055 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
signal transducer activity,
protein binding		 cytoplasm,
nucleus		 transcription,
circadian rhythm
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 662 TSLALPGKAESVASLTSQCSY CK1_epsilon 11232563
LTP
1.00
 MOD_CK1_1
 - -
0.31
 - medium
S 662 TSLALPGKAESVASLTSQCSY CK1_epsilon 11475410
LTP
1.00
 MOD_CK1_1
 - -
0.31
 - medium

Valid HTML 4.01 Transitional