Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Click on substrate name for additional information.

Substrate: Myosin-9 (myosin heavy chain, nonmuscle type A (NMMHC-A) (from PhosphoBase))

Seq-ID: P35579 [Homo sapiens]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-48057   IKKA_HUMAN
MINT-48117   IKKE_HUMAN
MINT-48214   NEMO_HUMAN
MINT-48485   M3K3_HUMAN
MINT-48678   NFKB1_HUMAN
MINT-49070   RIPK2_HUMAN
MINT-49443   TNR1B_HUMAN
MINT-72662   HS90B_HUMAN
MINT-6699369   TRPM7_HUMAN

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

protein homodimerization activity,
microfilament motor activity,
actin-dependent ATPase activity,
protein anchor,
ATP binding,
ADP binding,
calmodulin binding,
actin filament binding uropod,
actomyosin contractile ring,
stress fiber,
cytosol,
myosin complex,
nucleus,
ruffle,
cleavage furrow angiogenesis,
cytokinesis,
membrane protein ectodomain proteolysis,
actin cytoskeleton reorganization,
platelet formation,
protein transport,
integrin-mediated signaling pathway,
blood vessel endothelial cell migration,
regulation of cell shape,
monocyte differentiation,
actin filament-based movement,
leukocyte migration

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

T 1800 LKVKLQEMEGTVKSKYKASIT Chak1 18394644
LTP

0.66
- COIL
0.47
- medium

T 1800 LKVKLQEMEGTVKSKYKASIT Chak1 18675813
LTP

0.66
- COIL
0.47
- medium

S 1803 KLQEMEGTVKSKYKASITALE Chak1 18394644
LTP

1.00
- COIL
0.48
- medium

S 1808 EGTVKSKYKASITALEAKIAQ Chak1 18394644
LTP

0.81
- COIL
0.45
- medium

Substrate: Trpm7 (Ion channel)

Seq-ID: Q923J1 [Mus musculus]

Download: fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):
[show]

MINT-2524931   ACTB_MOUSE
MINT-2525581   MYH9_MOUSE

GO-Terms:
[show]

Molecular Function Cellular Component Biological Process

protein serine/threonine kinase activity,
calcium channel activity,
myosin binding,
metal ion binding,
ATP binding,
actin binding plasma membrane,
integral to membrane,
ruffle actomyosin structure organization,
calcium-dependent cell-matrix adhesion,
protein amino acid autophosphorylation

Conservation:

Click on table headers for sorting

Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.

S 1511 ASTEDSPEVDSKAALLPDWLR Chak1 15781465
LTP

0.16
- -
0.54
- -

S 1567 ERNNLMRLSQSIPFVPVPPRG Chak1 15781465
LTP

1.00
- -
0.41
1IA9 102.46%