Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

List of substrates found:

Developmental protein cactus
E(spl)
en
Fmr1
HmgZ
Nap1
Trl

Developmental protein cactus (developmental protein cactus (from PhosphoBase))

Seq-ID:

Q03017 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription factor binding	cytoplasm, neuromuscular junction	nervous system development, Toll signaling pathway, positive regulation of antifungal peptide biosynthetic process, dorsal/ventral axis specification, phagocytosis, engulfment, antifungal humoral response, hemopoiesis, dorsal appendage formation, innate immune response, response to DNA damage stimulus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	468	VTPPDSDYDSSDIEDLDDTKM	CkII_group_drome	9000511	LTP	1.00	MOD_CK2_1	-	-	0.60	-	medium

E(spl) (Enhancer of split m8 protein)

Seq-ID:

P13098 [Drosophila melanogaster]

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Interaction Network(s):

STRING

External Source(s):

MINT Interaction(s):

[show]

MINT-43534 GYS_DROME
MINT-44175 GROU_DROME

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, protein binding	nucleus	transcription, sensory organ precursor cell fate determination, regulation of R8 cell spacing in compound eye, imaginal disc-derived wing margin morphogenesis, mesoderm development, peripheral nervous system development, epidermal growth factor receptor signaling pathway, ectoderm development, Notch signaling pathway, regulation of transcription, DNA-dependent, dendrite morphogenesis

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	159	PLSPASSGYHSDCDSPAPSPQ	CkII_group_drome	15003630	LTP	1.00		-	-	0.77	-	low

en (Segmentation polarity homeobox protein engrailed)

Seq-ID:

P02836 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

MINT Interaction(s):

MINT-32927 CAND_DROME

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
transcription repressor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, protein binding	nucleus	anterior/posterior lineage restriction, imaginal disc, wing disc anterior/posterior pattern formation, axon guidance, imaginal disc-derived male genitalia development, transcription, genital disc anterior/posterior pattern formation, segment polarity determination, analia development, spiracle morphogenesis, open tracheal system, anterior head segmentation, trunk segmentation, regulation of transcription, DNA-dependent, anterior commissure morphogenesis, ventral midline development, posterior head segmentation, imaginal disc-derived female genitalia development, posterior compartment specification, neuroblast fate determination

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	394	PQPIPPPSAVSRDSGMESSDD	CkII_group_drome	7744743	LTP	0.18		-	-	0.94	-	medium
S	397	IPPPSAVSRDSGMESSDDTRS	CkII_group_drome	7744743	LTP	0.23		-	-	0.92	-	medium
S	401	SAVSRDSGMESSDDTRSETGS	CkII_group_drome	7744743	LTP	0.54		-	-	0.91	-	medium
S	402	AVSRDSGMESSDDTRSETGST	CkII_group_drome	7744743	LTP	0.44		-	-	0.91	-	medium

Seq-ID:

Q9NFU0 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

MINT Interaction(s):

MINT-38309 Y2199_DROME

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
identical protein binding, protein self-association, RNA binding	lipid particle, micro-ribonucleoprotein complex, RNA-induced silencing complex	axon guidance, locomotion, long-term memory, mushroom body development, negative regulation of dendrite morphogenesis, neuromuscular junction development, mitotic cell cycle, embryonic, male courtship behavior, olfactory learning, heterochromatin formation, pole cell formation, axonal fasciculation, visual perception, negative regulation of synaptogenesis, locomotor rhythm, negative regulation of translation, oocyte dorsal/ventral axis specification, synapse assembly, circadian sleep/wake cycle, sleep, regulation of cell proliferation, larval locomotory behavior, germ-line cyst formation, germarium-derived oocyte fate determination, dendrite morphogenesis, gene silencing by RNA, sperm axoneme assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	409	VTRRSERGYSSDIESVRSMRG	CkII_group_drome	12446764	LTP	0.24		-	-	0.72	-	low

HmgZ (High mobility group protein Z)

Seq-ID:

Q06943 [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
DNA binding	chromosome, nucleus

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	101	KPAKKAKKKESSEEEEEDESE	CkII_group_drome	10400623	LTP	0.57		-	-	0.82	-	low
S	102	PAKKAKKKESSEEEEEDESE	CkII_group_drome	10400623	LTP	0.00		-	-	0.82	-	low
S	110	ESSEEEEEDESE	CkII_group_drome	10400623	LTP	0.00		-	-	0.61	-	low

Nap1 (Nucleosome assembly protein NAP-1)

Seq-ID:

CG5330-PA [Drosophila melanogaster]

Download:

Interaction Network(s):

STRING

External Source(s):

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
histone binding	cytoplasm, nucleus	nucleosome assembly, regulation of transcription, DNA-dependent

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	118	EEKPQWKEPESSTDNEADAEH	CkII_group_drome	10547286	LTP	0.00		-	NAP	0.78	-	medium
T	120	KPQWKEPESSTDNEADAEHFR	CkII_group_drome	10547286	LTP	0.59		-	NAP	0.70	-	medium

Trl (Transcription factor GAGA)

Seq-ID:

Q08605 [Drosophila melanogaster]

Download:

Interaction Network(s):

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein heterodimerization activity, DNA binding, transcription activator activity, specific RNA polymerase II transcription factor activity, zinc ion binding	centromeric heterochromatin, polytene chromosome, euchromatin, nucleus	chromatin modification, transcription, cell division, syncytial blastoderm mitotic cell cycle, dosage compensation, imaginal disc-derived wing morphogenesis, positive regulation of transcription, DNA-dependent, chromatin assembly, oogenesis, protein oligomerization, mitosis, cell differentiation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	388	TTSGKKSSSGSSGSGSGALSS	CkII_group_drome	16023138	LTP	0.76		-	-	0.88	-	medium