a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	DRP-3 (Dihydropyrimidinase related protein-3)
Seq-ID:	ENSP00000343690 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	Molecular Function Cellular Component Biological Process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	636	GGTPAGSARGSPTRPNPPVRN	DYRK2	15466863	LTP	0.86		-	-	0.90	-	medium

Substrate:	p53 (Cellular tumor antigen p53)
Seq-ID:	P04637 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-13742   CHK2_HUMAN MINT-15878   UBP7_HUMAN MINT-16161   BRCA1_HUMAN MINT-16977   PARP1_HUMAN MINT-19990   PIN1_HUMAN MINT-24859   ASPP2_HUMAN MINT-45889   CEBPZ_HUMAN MINT-49767   ATM_HUMAN MINT-50577   SAE1_HUMAN MINT-56524   SP1_HUMAN MINT-58470   MED1_HUMAN MINT-58672   HNRL1_HUMAN MINT-60094   HIPK2_HUMAN MINT-61312   MK08_HUMAN MINT-61317   WWOX_HUMAN MINT-62206   PP1A_HUMAN MINT-63290   ARI2_HUMAN MINT-63365   KITH_HUMAN MINT-63497   ZNF24_HUMAN MINT-63537   IF2B_HUMAN MINT-63547   RAB4A_HUMAN MINT-63559   SAT1_HUMAN MINT-64119   STX5_HUMAN MINT-64188   MD2BP_HUMAN MINT-64748   K0087_HUMAN MINT-65132   HSPB1_HUMAN MINT-65272   MPH6_HUMAN MINT-68565   BMX_HUMAN MINT-74886   NPM_HUMAN MINT-74925   1433Z_HUMAN MINT-1795431   NMT1_HUMAN MINT-1891378   CDN1A_HUMAN MINT-1958329   CHK1_HUMAN MINT-2634790   RGRF1_HUMAN MINT-2858243   DVL2_HUMAN MINT-2866927   SCAM1_HUMAN MINT-3390028   KC1D_RAT MINT-3979604   P53_MOUSE MINT-4049689   NR4A1_HUMAN MINT-4052116   SYVN1_HUMAN MINT-4052873   GRP78_HUMAN MINT-4302642   HS71L_HUMAN MINT-4303978   XPO1_HUMAN MINT-4329805   TOPRS_HUMAN MINT-4793180   EGR1_HUMAN MINT-4793253   GSK3B_HUMAN MINT-4793489   PML_HUMAN MINT-5114724   ZN363_HUMAN MINT-5207405   HDAC8_HUMAN MINT-6540866   PSME3_HUMAN MINT-6540889   MDM2_HUMAN MINT-6628692   LT_SV40 MINT-6665320   CBP_HUMAN MINT-6701342   MAP1B_HUMAN MINT-7013631   PA1_HUMAN MINT-7013916   RYBP_HUMAN MINT-7103733   ANDR_HUMAN MINT-7144912   TOE1_HUMAN MINT-7222784   FRAP_HUMAN MINT-7263630   EP300_HUMAN MINT-7266250   PLK1_HUMAN MINT-7294020   FAK1_HUMAN MINT-7295816   IKKB_HUMAN MINT-7557644   GRP75_HUMAN MINT-7711943   1433S_HUMAN MINT-7717378   PHB_HUMAN MINT-7718917   SNAI1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process transcription activator activity, protease binding, DNA strand annealing activity, chromatin binding, copper ion binding, ATP binding, transcription factor binding, chaperone binding, zinc ion binding, histone acetyltransferase binding, promoter binding, sequence-specific DNA binding transcription factor activity, protein N-terminus binding, protein heterodimerization activity, protein phosphatase 2A binding, protein kinase binding, ubiquitin protein ligase binding nucleolus, nuclear matrix, insoluble fraction, protein complex, endoplasmic reticulum, PML body, mitochondrion positive regulation of gene-specific transcription from RNA polymerase II promoter, senescence, mitotic cell cycle G1/S DNA damage checkpoint, cell cycle arrest, regulation of mitochondrial membrane permeability, response to gamma radiation, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, response to tumor cell, ER overload response, DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis, interspecies interaction between organisms, Ras protein signal transduction, nucleotide-excision repair, protein tetramerization, cellular response to glucose starvation, negative regulation of helicase activity, negative regulation of cell growth, base-excision repair, activation of caspase activity by cytochrome c, cell aging
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	46	PSQAMDDLMLSPDDIEQWFTE	DYRK2	17349958	LTP	0.58		MAGI1 WW; PIN1 WW	-	0.63	-	-
S	46	PSQAMDDLMLSPDDIEQWFTE	DYRK2	19965871	LTP	0.58		MAGI1 WW; PIN1 WW	-	0.63	-	-