a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	eIF2 alpha (Translation regulatory protein)
Seq-ID:	P05198 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-2983884   IF4G2_HUMAN MINT-4507332   KPCA_HUMAN MINT-6740644   E2AK2_HUMAN MINT-7971492   DLG4_RAT
GO-Terms:	[show] Molecular Function Cellular Component Biological Process translation initiation factor activity, RNA binding, protein binding polysome, cytosol, eukaryotic translation initiation factor 2 complex
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	49	YNNIEGMILLSELSRRRIRSI	EIF2AK2	16288713	LTP	1.00		-	S1	0.11	1KL9	76.23%
S	52	IEGMILLSELSRRRIRSINKL	EIF2AK2	16179259	LTP	1.00		-	S1	0.10	-	-
S	52	IEGMILLSELSRRRIRSINKL	EIF2AK2	11432733	LTP	1.00		-	S1	0.10	-	-

Substrate:	P1/eIF-2A protein kinase (Serine/threonine kinase)
Seq-ID:	P19525 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-14552   CDC42_HUMAN MINT-3089429   NPM_HUMAN MINT-6740644   IF2A_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process eukaryotic translation initiation factor 2alpha kinase activity, double-stranded RNA binding, protein phosphatase type 2A regulator activity, ATP binding, protein binding intracellular protein amino acid autophosphorylation, interspecies interaction between organisms, negative regulation of osteoblast proliferation, response to virus
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	83	EILNKEKKAVSPLLLTTTNSS	EIF2AK2	11152499	LTP	1.00		-	-	0.39	-	-
T	88	EKKAVSPLLLTTTNSSEGLSM	EIF2AK2	11152499	LTP	0.18		-	-	0.42	-	-
T	89	KKAVSPLLLTTTNSSEGLSMG	EIF2AK2	11152499	LTP	0.93		-	-	0.41	-	-
T	90	KAVSPLLLTTTNSSEGLSMGN	EIF2AK2	11152499	LTP	1.00		-	-	0.39	-	-
S	242	LRNNQRKAKRSLAPRFDLPDM	EIF2AK2	9528799	LTP	0.11		-	-	0.55	-	-
S	242	LRNNQRKAKRSLAPRFDLPDM	EIF2AK2	8887659	LTP	0.11		-	-	0.55	-	-
S	242	LRNNQRKAKRSLAPRFDLPDM	EIF2AK2	11152499	LTP	0.11		-	-	0.55	-	-
T	255	PRFDLPDMKETKYTVDKRFGM	EIF2AK2	9528799	LTP	0.19		-	-	0.38	-	-
T	255	PRFDLPDMKETKYTVDKRFGM	EIF2AK2	8887659	LTP	0.19		-	-	0.38	-	-
T	255	PRFDLPDMKETKYTVDKRFGM	EIF2AK2	11152499	LTP	0.19		-	-	0.38	-	-
T	258	DLPDMKETKYTVDKRFGMDFK	EIF2AK2	11337501	LTP	1.00		-	-	0.38	2A19	18.49%
T	258	DLPDMKETKYTVDKRFGMDFK	EIF2AK2	9528799	LTP	1.00		-	-	0.38	2A19	18.49%
T	258	DLPDMKETKYTVDKRFGMDFK	EIF2AK2	8887659	LTP	1.00		-	-	0.38	2A19	18.49%
T	446	VTSLKNDGKRTRSKGTLRYMS	EIF2AK2	11337501	LTP	1.00		-	STYKc	0.44	2A19	54.11%
T	451	NDGKRTRSKGTLRYMSPEQIS	EIF2AK2	11337501	LTP	1.00		-	STYKc	0.52	2A19	69.86%

Substrate:	Small delta antigen (RNA binding)
Seq-ID:	Q6DUC3 [Hepatitis delta virus]
Download:	fasta csv
Interaction Network(s):	-
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process RNA binding host cell nucleus
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	177	FVPSMLDVPESPFTRTGEGLD	EIF2AK2	11152499	LTP	1.00		-	HDV_ag	0.77	-	low
T	180	SMLDVPESPFTRTGEGLDVRG	EIF2AK2	11152499	LTP	0.32		-	HDV_ag	0.78	-	low
T	182	LDVPESPFTRTGEGLDVRGNQ	EIF2AK2	11152499	LTP	1.00		-	HDV_ag	0.80	-	low