Click on substrate name for additional information.


Substrate: eIF2 alpha (Translation regulatory protein)
Seq-ID: P05198 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 49 YNNIEGMILLSELSRRRIRSI EIF2AK2 16288713
LTP
1.00
- S1
0.11
1KL9 76.23%
S 52 IEGMILLSELSRRRIRSINKL EIF2AK2 16179259
LTP
1.00
- S1
0.10
--
S 52 IEGMILLSELSRRRIRSINKL EIF2AK2 11432733
LTP
1.00
- S1
0.10
--

Substrate: P1/eIF-2A protein kinase (Serine/threonine kinase)
Seq-ID: P19525 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 83 EILNKEKKAVSPLLLTTTNSS EIF2AK2 11152499
LTP
1.00
- -
0.39
--
T 88 EKKAVSPLLLTTTNSSEGLSM EIF2AK2 11152499
LTP
0.18
- -
0.42
--
T 89 KKAVSPLLLTTTNSSEGLSMG EIF2AK2 11152499
LTP
0.93
- -
0.41
--
T 90 KAVSPLLLTTTNSSEGLSMGN EIF2AK2 11152499
LTP
1.00
- -
0.39
--
S 242 LRNNQRKAKRSLAPRFDLPDM EIF2AK2 9528799
LTP
0.11
- -
0.55
--
S 242 LRNNQRKAKRSLAPRFDLPDM EIF2AK2 8887659
LTP
0.11
- -
0.55
--
S 242 LRNNQRKAKRSLAPRFDLPDM EIF2AK2 11152499
LTP
0.11
- -
0.55
--
T 255 PRFDLPDMKETKYTVDKRFGM EIF2AK2 9528799
LTP
0.19
- -
0.38
--
T 255 PRFDLPDMKETKYTVDKRFGM EIF2AK2 8887659
LTP
0.19
- -
0.38
--
T 255 PRFDLPDMKETKYTVDKRFGM EIF2AK2 11152499
LTP
0.19
- -
0.38
--
T 258 DLPDMKETKYTVDKRFGMDFK EIF2AK2 11337501
LTP
1.00
- -
0.38
2A19 18.49%
T 258 DLPDMKETKYTVDKRFGMDFK EIF2AK2 9528799
LTP
1.00
- -
0.38
2A19 18.49%
T 258 DLPDMKETKYTVDKRFGMDFK EIF2AK2 8887659
LTP
1.00
- -
0.38
2A19 18.49%
T 446 VTSLKNDGKRTRSKGTLRYMS EIF2AK2 11337501
LTP
1.00
- STYKc
0.44
2A19 54.11%
T 451 NDGKRTRSKGTLRYMSPEQIS EIF2AK2 11337501
LTP
1.00
- STYKc
0.52
2A19 69.86%

Substrate: Small delta antigen (RNA binding)
Seq-ID: Q6DUC3 [Hepatitis delta virus]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
RNA binding host cell nucleus
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 177 FVPSMLDVPESPFTRTGEGLD EIF2AK2 11152499
LTP
1.00
- HDV_ag
0.77
- low
T 180 SMLDVPESPFTRTGEGLDVRG EIF2AK2 11152499
LTP
0.32
- HDV_ag
0.78
- low
T 182 LDVPESPFTRTGEGLDVRGNQ EIF2AK2 11152499
LTP
1.00
- HDV_ag
0.80
- low


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