List of substrates found:


Substrate: EPHB2 (Receptor for member of the ephrinB family)
Seq-ID: P54763 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-3388251   EPHA4_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transmembrane-ephrin receptor activity,
axon guidance receptor activity,
ATP binding,
receptor binding		 neuronal cell body,
integral to plasma membrane,
synapse		 negative regulation of axonogenesis,
retinal ganglion cell axon guidance,
positive regulation of long-term neuronal synaptic plasticity,
ephrin receptor signaling pathway,
learning,
camera-type eye morphogenesis,
central nervous system projection neuron axonogenesis,
peptidyl-tyrosine phosphorylation,
optic nerve morphogenesis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 604 SGHMTPGMKIYIDPFTYEDPN EphB2 10572014
LTP
1.00
 RASA_group SH2;
SH2D3C SH2		 -
0.30
 1JPA 15.60%
Y 610 GMKIYIDPFTYEDPNEAVREF EphB2 8622893
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2		 -
0.22
 1JPA 19.72%
Y 610 GMKIYIDPFTYEDPNEAVREF EphB2 10572014
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2		 -
0.22
 1JPA 19.72%
Y 610 GMKIYIDPFTYEDPNEAVREF EphB2 9632142
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2		 -
0.22
 1JPA 19.72%

Substrate: Ephrin B1 (Ligand of receptor tyrosine kinase)
Seq-ID: O73612 [Gallus gallus]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
Molecular FunctionCellular ComponentBiological Process
integral to membrane
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 312 CPHYEKVSGDYGHPVYIVQEM EphB2 11466320
LTP
0.99
 - -
0.20
 - medium
Y 317 KVSGDYGHPVYIVQEMPPQSP EphB2 11466320
LTP
0.99
 - -
0.29
 - medium
Y 331 EMPPQSPANIYYKV        EphB2 11466320
LTP
1.00
 - -
0.23
 - medium

Substrate: Ephrin-B2 precursor (Binds to the receptor tyrosine kinases EPHB4 and EPHA3)
Seq-ID: P52799 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ephrin receptor binding integral to plasma membrane nervous system development,
cell-cell signaling,
interspecies interaction between organisms,
cell differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 304 RTADSVFCPHYEKVSGDYGHP EphB2 15096211
LTP
1.00
 NCK SH2 -
0.23
 - medium

Substrate: Ras-related protein (GTPase)
Seq-ID: P10301 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-7245826   SRC_HUMAN
MINT-7247122   FYN_HUMAN
MINT-7251046   NCK1_HUMAN
MINT-7251718   P85A_HUMAN
MINT-7252546   PLCG1_HUMAN
MINT-7253338   GRB2_HUMAN
MINT-7254262   CRK_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
GDP binding,
GTPase activity,
GTP binding,
protein binding		 plasma membrane,
intracellular		 Ras protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 66 SDYDPTIEDSYTKICSVDGIP EphB2 10570155
LTP
1.00
 - RAS
0.32
 2FN4 17.03%

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