a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	Shc ( Adaptor molecule)
Seq-ID:	P29353 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-13959   DDR2_HUMAN MINT-14688   GAB2_HUMAN MINT-15243   LYN_HUMAN MINT-15425   FYN_HUMAN MINT-15946   FCGR1_HUMAN MINT-16179   SHIP1_HUMAN MINT-16513   LCP2_HUMAN MINT-17269   SRC_CHICK MINT-17501   P85A_HUMAN MINT-49636   CADH5_HUMAN MINT-49637   VGFR2_HUMAN MINT-49660   A4_HUMAN MINT-60978   CBL_HUMAN MINT-60980   ZAP70_HUMAN MINT-60981   RET_HUMAN MINT-61536   ERBB4_HUMAN MINT-61537   GRB2_HUMAN MINT-74732   EGFR_HUMAN MINT-74737   ERBB2_HUMAN MINT-74738   ERBB3_HUMAN MINT-1782423   SOS1_HUMAN MINT-2738306   JAK2_MOUSE MINT-7714840   IQGA1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process epidermal growth factor receptor binding, insulin-like growth factor receptor binding, insulin receptor binding, phospholipid binding, transmembrane receptor protein tyrosine kinase adaptor protein activity mitochondrial matrix, Shc-EGFR complex, cytosol positive regulation of DNA replication, positive regulation of cell proliferation, regulation of growth, regulation of epidermal growth factor receptor activity, epidermal growth factor receptor signaling pathway, activation of MAPK activity, Ras protein signal transduction, insulin receptor signaling pathway
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	349	EEEEEPPDHQYYNDFPGKEPP	FLT4	9927207	LTP	1.00		GRAP2 SH2; GRB2 SH2; INPP5D SH2	-	0.86	-	-
Y	350	EEEEPPDHQYYNDFPGKEPPL	FLT4	9927207	LTP	1.00		GRB2 SH2; INPP5D SH2	-	0.85	-	-
Y	427	PGRELFDDPSYVNVQNLDKAR	FLT4	9927207	LTP	0.99		GRAP2 SH2; GRB2 SH2; INPP5D SH2	-	0.62	-	-

Substrate:	VEGFR3 long form (Vascular endothelial growth factor receptor)
Seq-ID:	ENSP00000261937 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process ATP binding integral to plasma membrane protein amino acid phosphorylation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	1337	RGGQVFYNSEYGELSEPSEED	FLT4	12881528	LTP	0.18		-	-	0.63	-	medium
Y	1363	ARVTFFTDNSY	FLT4	12881528	LTP	0.00		-	-	0.25	-	medium