a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	Bcr (Breakpoint cluster region protein)
Seq-ID:	P11274 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-69534   AT2B1_HUMAN MINT-69536   CLH1_HUMAN MINT-69537   CFTR_HUMAN MINT-69540   ZO2_HUMAN MINT-69542   RGS12_HUMAN MINT-4961172   AFAD_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process Rho guanyl-nucleotide exchange factor activity, protein serine/threonine kinase activity, ATP binding, GTPase activator activity intracellular protein amino acid phosphorylation, signal transduction, regulation of Rho protein signal transduction
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	177	QPGADAEKPFYVNVEFHHERG	Fes	8955135	LTP	0.75		ABL1 SH2; FES SH2; GRAP SH2; GRB2 SH2; PTPN11 SH2	-	0.68	-	medium
Y	177	QPGADAEKPFYVNVEFHHERG	Fes	10405761	LTP	0.75		ABL1 SH2; FES SH2; GRAP SH2; GRB2 SH2; PTPN11 SH2	-	0.68	-	medium
Y	246	SESSCGVDGDYEDAELNPRFL	Fes	8955135	LTP	1.00		ABL1 SH2; GRB10 SH2; GRB2 SH2	-	0.57	-	medium
Y	276	GSRPPWPPLEYQPYQSIYVGG	Fes	8955135	LTP	0.00		ABL1 SH2; GRB10 SH2; GRB2 SH2; SHC1 SH2; SHC_group SH2	-	0.58	-	medium
Y	279	PPWPPLEYQPYQSIYVGGMME	Fes	8955135	LTP	1.00		ABL1 SH2; GRB10 SH2; GRB2 SH2; SHC1 SH2; SHC_group SH2	-	0.58	-	medium
Y	283	PLEYQPYQSIYVGGMMEGEGK	Fes	8955135	LTP	1.00		ABL1 SH2; GRB10 SH2; GRB2 SH2; SHC1 SH2; SHC_group SH2	-	0.61	-	medium

Substrate:	C-Fes (Cytoplasmic tyrosine kinase)
Seq-ID:	P07332 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-74535   EGFR_HUMAN MINT-6380786   EZRI_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process non-membrane spanning protein tyrosine kinase activity, ATP binding, protein binding cytosol peptidyl-tyrosine phosphorylation, multicellular organismal development, cell proliferation
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	713	GMSREEADGVYAASGGLRQVP	Fes	8663427	LTP	1.00		-	TyrKc	0.29	3BKB	16.59%
Y	811	PGQRPSFSTIYQELQSIRKRH	Fes	7687763	LTP	0.23		SYK SH2	TyrKc	0.34	3BKB	31.44%

Substrate:	CD31 (Adhesion molecule)
Seq-ID:	Q08481 [Mus musculus]
Download:	fasta csv
Interaction Network(s):	-
External Source(s):
MINT Interaction(s):	-
GO-Terms:	[show] Molecular Function Cellular Component Biological Process smooth muscle contractile fiber, cell junction, integral to membrane, soluble fraction, membrane raft regulation of cell migration, Rho protein signal transduction, cell adhesion, wound healing
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	702	ALGTRATETVYSEIRKVDPNL	Fes	16731527	LTP	1.00		-	-	0.57	-	medium
Y	717	KVDPNLMENRYSRTEGSLNGT	Fes	16731527	LTP	1.00		-	-	0.75	-	medium