List of substrates found:


Substrate: c-Jun (c-Jun (Transcription factor AP-1))
Seq-ID: P05412 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14077   DDX21_HUMAN
MINT-68803   VE7_HPV16
MINT-68804   FOS_HUMAN
MINT-6628041   ATF2_HUMAN
MINT-6628056   CITE1_HUMAN
MINT-7148314   MK08_HUMAN
MINT-7148323   MK09_HUMAN
MINT-7148332   MK10_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription repressor activity,
R-SMAD binding,
RNA polymerase II transcription factor activity, enhancer binding,
Rho GTPase activator activity,
transcription coactivator activity,
promoter binding		 SMAD protein nuclear translocation,
positive regulation by host of viral transcription,
SMAD protein signal transduction,
negative regulation of DNA binding,
transforming growth factor beta receptor signaling pathway,
positive regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 239 PQTVPEMPGETPPLSPIDMES GSK-3_alpha 1956339
LTP
0.27
 MOD_GSK3_1
 PIN1 WW Jun
0.90
 --
T 239 PQTVPEMPGETPPLSPIDMES GSK-3_alpha 1846781
LTP
0.27
 MOD_GSK3_1
 PIN1 WW Jun
0.90
 --
S 243 PEMPGETPPLSPIDMESQERI GSK-3_alpha 1846781
LTP
1.00
 MOD_GSK3_1
 PIN1 WW -
0.87
 --

Substrate: c-myc (Myc proto-oncogene protein (c-myc))
Seq-ID: P01106 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-25075   MAX_HUMAN
MINT-6628157   VE7_HPV16
MINT-7040788   AXN1_HUMAN
MINT-7306800   BIN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription activator activity,
E-box binding,
sequence-specific DNA binding transcription factor activity		 nucleolus branching involved in ureteric bud morphogenesis,
cellular iron ion homeostasis,
cell cycle arrest,
response to drug,
cell proliferation,
positive regulation of metanephric cap mesenchymal cell proliferation,
regulation of telomere maintenance
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 58 DIWKKFELLPTPPLSPSRRSG GSK-3_alpha 14563837
LTP
1.00
 MOD_GSK3_1
 - Myc_N
0.38
 - low

Substrate: Cyclin E1 (Cell cycle control protein)
Seq-ID: P24864 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14269   FBXW7_HUMAN
MINT-1788668   FOXM1_HUMAN
MINT-2635177   CDN1A_HUMAN
MINT-2983466   CDK2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
androgen receptor binding,
transcription coactivator activity		 cytosol,
nucleoplasm		 cell division,
positive regulation of transcription, DNA-dependent,
G1/S transition of mitotic cell cycle,
androgen receptor signaling pathway
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 395 RASPLPSGLLTPPQSGKKQSS GSK-3_alpha 14536078
LTP
1.00
 MOD_GSK3_1
 - -
0.77
 --

Substrate: MKI67IP (protein binding, RNA binding)
Seq-ID: Q9BYG3 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-50550   KI67_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
nucleotide binding,
RNA binding,
protein binding		 condensed nuclear chromosome,
cytoplasm,
nucleolus,
nucleoplasm		 protein complex assembly,
rRNA transcription,
rRNA metabolic process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 230 TLDTPEKTVDSQGPTPVCTPT GSK-3_alpha 16244663
LTP
1.00
 MOD_GSK3_1
 - -
0.68
 - medium
T 234 PEKTVDSQGPTPVCTPTFLER GSK-3_alpha 16244663
LTP
1.00
 MOD_GSK3_1
 MKI67 FHA -
0.65
 - medium

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