List of substrates found:


Substrate: Forkhead box protein O3A (Forkhead box protein O3A (Forkhead in rhabdomyosarcoma-like 1))
Seq-ID: O43524 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-14323   1433Z_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
protein kinase binding,
transcription activator activity,
sequence-specific DNA binding transcription factor activity		 cytosol,
nucleus		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
transcription,
apoptosis,
positive regulation of erythrocyte differentiation,
positive regulation of transcription from RNA polymerase II promoter
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 644 DADGLDFNFDSLISTQNVVGL IKK_beta 15084260
LTP
0.26
 - -
0.26
 --

Substrate: NF-kappa-B essential modulator (Serine/threonine kinase)
Seq-ID: O88522 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
MINT-7262667   UBIQ_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
metal ion binding nucleus transcription,
activation of NF-kappaB-inducing kinase activity,
B cell homeostasis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 375 PAHHSFHLALSNQRRSPPEEP IKK_beta 11971901
LTP
0.49
 - -
0.73
 - medium

Substrate: NF-kappa-B essential modulator (Serine/threonine kinase)
Seq-ID: Q9Y6K9 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-15857   TNAP3_HUMAN
MINT-16075   RIPK1_HUMAN
MINT-16575   RIPK2_HUMAN
MINT-47843   IKBA_HUMAN
MINT-47855   IKBB_HUMAN
MINT-48127   SYVC_HUMAN
MINT-48129   GOGA3_HUMAN
MINT-48131   HS71L_HUMAN
MINT-48132   GRP78_HUMAN
MINT-48133   DREB_HUMAN
MINT-48134   HSP7C_HUMAN
MINT-48137   IKKA_HUMAN
MINT-48140   ADT2_HUMAN
MINT-48142   GRP75_HUMAN
MINT-48144   SYMC_HUMAN
MINT-48146   RS10_HUMAN
MINT-48147   RLA2_HUMAN
MINT-48149   XPO1_HUMAN
MINT-48151   MYO1C_HUMAN
MINT-48152   EPIPL_HUMAN
MINT-48153   RS3_HUMAN
MINT-48154   TIF1B_HUMAN
MINT-48156   RS20_HUMAN
MINT-48157   KINH_HUMAN
MINT-48158   CDC37_HUMAN
MINT-48159   SYIC_HUMAN
MINT-48160   GBLP_HUMAN
MINT-48161   EF1A2_HUMAN
MINT-48162   MSH2_HUMAN
MINT-48166   MCM7_HUMAN
MINT-48167   MYH10_HUMAN
MINT-48168   PYR1_HUMAN
MINT-48169   CALX_HUMAN
MINT-48170   ACTG_HUMAN
MINT-48171   ESYT1_HUMAN
MINT-48173   CLH1_HUMAN
MINT-48174   IKKB_HUMAN
MINT-48177   RS14_HUMAN
MINT-48181   DYHC1_HUMAN
MINT-48186   CALM_HUMAN
MINT-48187   UTP20_HUMAN
MINT-48188   RLA0_HUMAN
MINT-48190   HS90A_HUMAN
MINT-48192   FAS_HUMAN
MINT-48193   TBB5_HUMAN
MINT-48195   ECM29_HUMAN
MINT-48196   TBB4_HUMAN
MINT-48198   RS27_HUMAN
MINT-48199   A16L1_HUMAN
MINT-48204   KCC2D_HUMAN
MINT-48205   USO1_HUMAN
MINT-48206   1433Z_HUMAN
MINT-48207   FLNA_HUMAN
MINT-48208   IPO7_HUMAN
MINT-48209   SMC4_HUMAN
MINT-48213   GCN1L_HUMAN
MINT-48214   MYH9_HUMAN
MINT-48215   HNRPU_HUMAN
MINT-48218   VIME_HUMAN
MINT-48220   PARP1_HUMAN
MINT-48221   ADT3_HUMAN
MINT-48222   CCAR1_HUMAN
MINT-48223   COPA_HUMAN
MINT-48224   TBK1_HUMAN
MINT-48225   PP1G_HUMAN
MINT-48226   PP1B_HUMAN
MINT-48227   TXLNA_HUMAN
MINT-48228   PUR2_HUMAN
MINT-48229   PRKDC_HUMAN
MINT-48230   MYL6_HUMAN
MINT-48232   XPO7_HUMAN
MINT-48235   RS3A_HUMAN
MINT-48239   HS90B_HUMAN
MINT-48240   ML12A_HUMAN
MINT-48241   CH60_HUMAN
MINT-48244   SET_HUMAN
MINT-48245   MYO1D_HUMAN
MINT-48371   M3K3_HUMAN
MINT-48638   NFKB1_HUMAN
MINT-48692   NFKB2_HUMAN
MINT-48784   M3K14_HUMAN
MINT-2844414   SQSTM_HUMAN
MINT-4652797   M3K7_HUMAN
MINT-6177604   MALT1_HUMAN
MINT-6978609   ATM_HUMAN
MINT-6978686   ATR_HUMAN
MINT-6978719   ATRIP_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein domain specific binding,
metal ion binding,
signal transducer activity		 nucleus transcription,
immune response,
interspecies interaction between organisms,
positive regulation of NF-kappaB transcription factor activity,
response to DNA damage stimulus,
T cell receptor signaling pathway,
induction of apoptosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 31 AADQDVLGEESPLGKPAMLHL IKK_beta 12657630
LTP
1.00
 - -
0.67
 --
S 43 LGKPAMLHLPSEQGAPETLQR IKK_beta 12657630
LTP
1.00
 - -
0.64
 --
S 376 APLPPAPAYLSSPLALPSQRR IKK_beta 12657630
LTP
1.00
 - -
0.62
 --

Substrate: Nuclear factor NF-kappa-B p105 subunit (Nuclear factor NF-kappa-B p105 subunit)
Seq-ID: P19838 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-47827   M3K8_HUMAN
MINT-47861   IKBB_HUMAN
MINT-48545   TPR_HUMAN
MINT-48546   KCRB_HUMAN
MINT-48547   CLH1_HUMAN
MINT-48555   VIME_HUMAN
MINT-48556   ADT3_HUMAN
MINT-48557   DESP_HUMAN
MINT-48560   JIP4_HUMAN
MINT-48561   COPB2_HUMAN
MINT-48636   BAG2_HUMAN
MINT-48638   NEMO_HUMAN
MINT-48639   HS71L_HUMAN
MINT-48640   GRP78_HUMAN
MINT-48641   HSP7C_HUMAN
MINT-48642   HNRPF_HUMAN
MINT-48643   IKKA_HUMAN
MINT-48644   ADT2_HUMAN
MINT-48645   GRP75_HUMAN
MINT-48646   RUVB2_HUMAN
MINT-48648   IMA3_HUMAN
MINT-48650   DNJA1_HUMAN
MINT-48651   IMA4_HUMAN
MINT-48653   C1QBP_HUMAN
MINT-48654   EF1A2_HUMAN
MINT-48655   MATR3_HUMAN
MINT-48656   IKBA_HUMAN
MINT-48659   MYH10_HUMAN
MINT-48660   PYR1_HUMAN
MINT-48663   ACTG_HUMAN
MINT-48665   STUB1_HUMAN
MINT-48666   REL_HUMAN
MINT-48669   TBB6_HUMAN
MINT-48670   CALM_HUMAN
MINT-48671   NONO_HUMAN
MINT-48672   TBB5_HUMAN
MINT-48673   TBB4_HUMAN
MINT-48675   K1967_HUMAN
MINT-48677   DNJA3_HUMAN
MINT-48678   MYH9_HUMAN
MINT-48679   RS8_HUMAN
MINT-48680   SFPQ_HUMAN
MINT-48682   HS90A_HUMAN
MINT-48684   PRKDC_HUMAN
MINT-48685   MYL6_HUMAN
MINT-48687   HNRPM_HUMAN
MINT-48688   HS90B_HUMAN
MINT-48689   ML12A_HUMAN
MINT-48724   NFKB2_HUMAN
MINT-48996   RELB_HUMAN
MINT-50169   HDAC1_HUMAN
MINT-7023862   CTNB1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
promoter binding,
sequence-specific DNA binding transcription factor activity,
protein binding		 cytosol,
I-kappaB/NF-kappaB complex,
nucleoplasm		 negative regulation of gene-specific transcription from RNA polymerase II promoter,
transcription from RNA polymerase II promoter,
positive regulation of transcription,
negative regulation of cellular protein metabolic process,
apoptosis,
anti-apoptosis,
negative regulation of cholesterol transport,
membrane protein intracellular domain proteolysis,
positive regulation of lipid storage,
signal transduction,
inflammatory response,
positive regulation of macrophage derived foam cell differentiation,
negative regulation of vitamin D biosynthetic process,
negative regulation of calcidiol 1-monooxygenase activity
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 923 QQIDELRDSDSVCDSGVETSF IKK_beta 10469655
LTP
0.09
 - -
0.49
 --
S 927 ELRDSDSVCDSGVETSFRKLS IKK_beta 10469655
LTP
1.00
 - -
0.41
 --

Substrate: p65 (Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit), RelA)
Seq-ID: Q04206 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-50016   IKBA_MOUSE
MINT-50017   IKBB_MOUSE
MINT-50025   KAPCA_HUMAN
MINT-50073   KS6A5_HUMAN
MINT-50084   KPCZ_HUMAN
MINT-50090   CSK21_HUMAN
MINT-50107   IKKA_HUMAN
MINT-50167   IKKB_HUMAN
MINT-50171   HDAC1_HUMAN
MINT-50175   KAT2B_HUMAN
MINT-50178   EP300_HUMAN
MINT-50179   HDAC3_HUMAN
MINT-58638   NCF1_HUMAN
MINT-62399   TF2B_HUMAN
MINT-2834593   NCOA3_HUMAN
MINT-6166971   OGT1_HUMAN
MINT-7235700   ASPP2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription repressor activity,
transcription repressor binding,
identical protein binding,
protein kinase binding,
ubiquitin protein ligase binding,
transcription activator binding,
transcription activator activity,
RNA polymerase II transcription factor activity, enhancer binding,
promoter binding,
protein N-terminus binding,
phosphate binding,
NF-kappaB binding		 cytosol,
transcription factor complex		 transcription,
positive regulation of I-kappaB kinase/NF-kappaB cascade,
cytokine-mediated signaling pathway,
anti-apoptosis,
defense response to virus,
membrane protein intracellular domain proteolysis,
cellular defense response,
inflammatory response,
nucleotide-binding oligomerization domain containing 2 signaling pathway,
response to interleukin-1,
interspecies interaction between organisms,
positive regulation of NF-kappaB transcription factor activity,
positive regulation of transcription from RNA polymerase II promoter,
response to UV-B,
negative regulation of gene-specific transcription
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 536 GLLSGDEDFSSIADMDFSALL IKK_beta 15128824
LTP
0.93
 - -
0.35
 --
S 536 GLLSGDEDFSSIADMDFSALL IKK_beta 15489227
LTP
0.93
 - -
0.35
 --

Substrate: p65 (Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit), RelA)
Seq-ID: Q04207 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19530   IKBA_MOUSE
MINT-19560   IKBB_MOUSE
MINT-7288484   UBIQ_MOUSE
MINT-7288511   CUL2_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
transcription activator activity,
RNA polymerase II transcription factor activity, enhancer binding,
chromatin binding		 cytosol transcription,
organ morphogenesis,
negative regulation of protein catabolic process,
hair follicle development,
liver development,
positive regulation of interleukin-12 biosynthetic process,
response to muramyl dipeptide
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 534 NGLSGDEDFSSIADMDFSALL IKK_beta 16135789
LTP
0.21
 - -
0.40
 --

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