List of substrates found:


Substrate: IKB-alpha (Major histocompatibility complex enhancer-binding protein MAD3)
Seq-ID: P25963 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 32 KERLLDDRHDSGLDSMKDEEY IKK_group 10723127
LTP
1.00
- -
0.63
--
S 32 KERLLDDRHDSGLDSMKDEEY IKK_group 10882136
LTP
1.00
- -
0.63
--
S 36 LDDRHDSGLDSMKDEEYEQMV IKK_group 10882136
LTP
1.00
- -
0.65
--
S 36 LDDRHDSGLDSMKDEEYEQMV IKK_group 9346484
LTP
1.00
- -
0.65
--

Substrate: IKK-beta (Inhibitor of nuclear factor kappa B kinase beta subunit)
Seq-ID: O14920 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 177 LGYAKELDQGSLCTSFVGTLQ IKK_group 10779355
LTP
0.94
- STYKc
0.08
--
S 181 KELDQGSLCTSFVGTLQYLAP IKK_group 10195894
LTP
0.96
- STYKc
0.08
--
S 670 IACSKVRGPVSGSPDSMNASR IKK_group 10195894
LTP
0.19
- -
0.55
--
S 672 CSKVRGPVSGSPDSMNASRLS IKK_group 10195894
LTP
1.00
- -
0.63
--
S 675 VRGPVSGSPDSMNASRLSQPG IKK_group 10195894
LTP
0.30
- -
0.70
--
S 682 SPDSMNASRLSQPGQLMSQPS IKK_group 10195894
LTP
0.19
- -
0.73
--
S 689 SRLSQPGQLMSQPSTASNSLP IKK_group 10195894
LTP
0.20
- -
0.70
--
S 692 SQPGQLMSQPSTASNSLPEPA IKK_group 10195894
LTP
0.79
- -
0.75
--
S 695 GQLMSQPSTASNSLPEPAKKS IKK_group 10195894
LTP
0.17
- -
0.75
--
S 697 LMSQPSTASNSLPEPAKKSEE IKK_group 10195894
LTP
0.31
- -
0.74
--
S 705 SNSLPEPAKKSEELVAEAHNL IKK_group 10195894
LTP
0.12
- -
0.56
3BRV 95.08%
S 733 IQDTVREQDQSFTALDWSWLQ IKK_group 10195894
LTP
1.00
- -
0.41
3BRV 40.98%
S 740 QDQSFTALDWSWLQTEEEEHS IKK_group 10195894
LTP
1.00
- -
0.44
3BRV 59.84%
S 750 SWLQTEEEEHSCLEQAS     IKK_group 10195894
LTP
0.19
- -
0.52
--

Substrate: Insulin receptor substrate 1 (After phosphorylation by insulin receptor binds to various cellular proteins containing SH2 domains.)
Seq-ID: P35568 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 268 RAMSDEFRPRSKSQSSSNCSN IKK_group 12351658
LTP
1.00
- -
0.69
--
S 270 MSDEFRPRSKSQSSSNCSNPI IKK_group 12351658
LTP
1.00
YWHAG 14-3-3;
YWHAZ 14-3-3
-
0.69
--
S 272 DEFRPRSKSQSSSNCSNPISV IKK_group 12351658
LTP
1.00
- -
0.67
--
S 274 FRPRSKSQSSSNCSNPISVPL IKK_group 12351658
LTP
1.00
- -
0.69
--
S 307 VGLTRRSRTESITATSPASMV IKK_group 12351658
LTP
1.00
- -
0.78
--
S 312 RSRTESITATSPASMVGGKPG IKK_group 12351658
LTP
1.00
- -
0.80
--
S 341 DGEGTMSRPASVDGSPVSPST IKK_group 12351658
LTP
0.96
- -
0.90
--
S 345 TMSRPASVDGSPVSPSTNRTH IKK_group 12351658
LTP
1.00
- -
0.90
--
S 527 LDNRFRKRTHSAGTSPTITHQ IKK_group 12351658
LTP
1.00
- -
0.82
--
S 531 FRKRTHSAGTSPTITHQKTPS IKK_group 12351658
LTP
1.00
- -
0.89
--

Substrate: Insulin receptor substrate 2 (Adaptor molecule)
Seq-ID: Q9Y4H2 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 304 LKELFEFRPRSKSQSSGSSAT IKK_group 12351658
LTP
1.00
- -
0.53
- medium
S 306 ELFEFRPRSKSQSSGSSATHP IKK_group 12351658
LTP
1.00
- -
0.58
- medium
S 384 GAAAAGARPVSVAGSPLSPGP IKK_group 12351658
LTP
1.00
- -
0.74
- medium
S 388 AGARPVSVAGSPLSPGPVRAP IKK_group 12351658
LTP
1.00
- -
0.78
- medium
S 577 LDRGLRKRTYSLTTPARQRPV IKK_group 12351658
LTP
1.00
- -
0.77
- medium

Substrate: NF-kappa-B essential modulator (Serine/threonine kinase)
Seq-ID: O88522 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 369 PPLLPAPAHHSFHLALSNQRR IKK_group 11971901
LTP
1.00
- -
0.61
- medium

Substrate: Nuclear factor NF-kappa-B p105 subunit (Nuclear factor NF-kappa-B p105 subunit)
Seq-ID: P19838 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 923 QQIDELRDSDSVCDSGVETSF IKK_group 11158290
LTP
0.09
- -
0.49
--
S 927 ELRDSDSVCDSGVETSFRKLS IKK_group 11158290
LTP
1.00
- -
0.41
--
S 927 ELRDSDSVCDSGVETSFRKLS IKK_group 12482991
LTP
1.00
- -
0.41
--

Substrate: p65 (Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit), RelA)
Seq-ID: Q04206 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

Click here to enable the multiple sequence alignment viewer Jalview (requires Java browser plugin).
Try the unsigned version of the java plugin if the first link does not work for you...
Alternatively, you can download the alignment, conservation features, and phosphosite features to load into Jalview Desktop.
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 536 GLLSGDEDFSSIADMDFSALL IKK_group 10521409
LTP
0.93
- -
0.35
--

Valid HTML 4.01 Transitional