List of substrates found:


Substrate: CCR2 (Monocyte chemoattractant protein 1 receptor)
Seq-ID: P41597 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 139 FFIILLTIDRYLAIVHAVFAL JAK2 9670957
LTP
1.00
- 7tm_1
0.00
- low

Substrate: CTLA-4 (CD152 antigen)
Seq-ID: P09793 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
external side of plasma membrane,
integral to membrane
immune response
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 201 KKRSPLTTGVYVKMPPTEPEC JAK2 10842319
LTP
1.00
- -
0.36
- low

Substrate: CTLA-4 (CD152 antigen)
Seq-ID: P16410 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 201 KKRSPLTTGVYVKMPPTEPEC JAK2 10842319
LTP
1.00
PIK3R1 SH2;
PTPN11 SH2
-
0.37
- low

Substrate: Epo-R (Receptor for erythropoietin, a major activator of erythropoiesis)
Seq-ID: P19235 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
erythropoietin receptor activity extracellular region,
integral to plasma membrane
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 368 PVGSEHAQDTYLVLDKWLLPR JAK2 10579919
LTP
1.00
CISH SH2;
INPP5D SH2;
PLCG2 SH2;
STAT5 SH2;
SYK SH2
-
0.32
- low

Substrate: GH-R (Growth hormon receptor)
Seq-ID: P10912 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 332 VNTILAIHDSYKPEFHSDDSW JAK2 9121492
LTP
0.90
- -
0.23
- low
Y 487 NPSSLSNIDFYAQVSDITPAG JAK2 9121492
LTP
1.00
CISH SH2;
GRB10 SH2;
SOCS2 SH2;
STAT3 SH2;
STAT5 SH2
-
0.42
- low

Substrate: JAK2 (Cytoplasmic tyrosine kinase)
Seq-ID: O60674 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 1007 LTKVLPQDKEYYKVKEPGESP JAK2 9111318
LTP
1.00
SOCS1 SH2;
SOCS3 SH2
TyrKc
0.27
3E62 61.14%
Y 1008 TKVLPQDKEYYKVKEPGESPI JAK2 11818507
LTP
1.00
- TyrKc
0.25
3E62 40.17%

Substrate: JAK2 (Cytoplasmic tyrosine kinase)
Seq-ID: Q62120 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 221 PKCVRAKIQDYHILTRKRIRY JAK2 15143187
LTP
0.57
- B41
0.08
- medium
Y 221 PKCVRAKIQDYHILTRKRIRY JAK2 15143188
LTP
0.57
- B41
0.08
- medium
Y 570 FKGVRREVGDYGQLHKTEVLL JAK2 15143187
LTP
0.20
- STYKc
0.16
- medium
Y 570 FKGVRREVGDYGQLHKTEVLL JAK2 16705159
LTP
0.20
- STYKc
0.16
- medium
Y 570 FKGVRREVGDYGQLHKTEVLL JAK2 15143188
LTP
0.20
- STYKc
0.16
- medium
Y 813 RDLNSLFTPDYELLTENDMLP JAK2 15121872
LTP
0.95
- -
0.28
- medium
Y 1007 LTKVLPQDKEYYKVKEPGESP JAK2 9111318
LTP
1.00
- TyrKc
0.27
- medium
Y 1007 LTKVLPQDKEYYKVKEPGESP JAK2 15143187
LTP
1.00
- TyrKc
0.27
- medium
Y 1007 LTKVLPQDKEYYKVKEPGESP JAK2 15530433
LTP
1.00
- TyrKc
0.27
- medium
Y 1008 TKVLPQDKEYYKVKEPGESPI JAK2 9111318
LTP
1.00
- TyrKc
0.25
- medium
Y 1008 TKVLPQDKEYYKVKEPGESPI JAK2 15530433
LTP
1.00
- TyrKc
0.25
- medium

Substrate: SH2-B beta signaling protein (Unclassified)
Seq-ID: ENSP00000352232 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
signal transducer activity cytoplasm,
nucleus,
membrane
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 439 ESNDRLSQGAYGGLSDRPSAS JAK2 12551917
LTP
0.10
- -
0.71
- medium
Y 494 TGTVHPLSAPYPPLDTPETAT JAK2 12551917
LTP
0.14
- -
0.76
- medium

Substrate: STAT 1 (Transcription factor)
Seq-ID: P42224 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 701 MELDGPKGTGYIKTELISVSE JAK2 11438544
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%
Y 701 MELDGPKGTGYIKTELISVSE JAK2 14978237
LTP
1.00
STAT1 SH2;
STAT2 SH2
-
0.47
1BF5 139.74%

Substrate: STAT 3 (Transcription factor)
Seq-ID: P40763 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 705 PEADPGSAAPYLKTKFICVTP JAK2 9582023
LTP
0.63
STAT3 SH2 -
0.34
1BG1 138.86%

Substrate: STAT 5 (Transcription factor)
Seq-ID: P42229 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 694 TPVLAKAVDGYVKPQIKQVVP JAK2 11641791
LTP
0.25
CRKL SH2;
PTPN11 SH2;
STAT5 SH2
SH2
0.20
- medium

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