List of substrates found:


Substrate: Bcl-2-like protein 11 (Unclassified)
Seq-ID: O43521 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-68751   MCL1_HUMAN
MINT-6629252   BCL2_HUMAN
MINT-7034069   BAX_HUMAN
MINT-7034091   BAD_HUMAN
MINT-7965699   MCL1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein binding plasma membrane,
mitochondrion,
cytosol,
endomembrane system		 induction of apoptosis by extracellular signals,
activation of pro-apoptotic gene products
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 104 SGYFSFDTDRSPAPMSCDKST JNK_group 12591950
LTP
1.00
 MOD_ProDKin_1
 - -
0.58
 - low
T 116 APMSCDKSTQTPSPPCQAFNH JNK_group 12591950
LTP
1.00
 MOD_ProDKin_1
 - -
0.61
 - low
S 118 MSCDKSTQTPSPPCQAFNHYL JNK_group 12591950
LTP
1.00
 MOD_ProDKin_1
 - -
0.55
 - low

Substrate: ETS domain protein Elk-3 (Transcription factor)
Seq-ID: P41970 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-7250482   NCK1_HUMAN
MINT-7251622   P85A_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
purine-rich negative regulatory element binding,
transcription corepressor activity,
sequence-specific DNA binding transcription factor activity		 mitochondrion,
nucleus		 transcription,
signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 357 LSSIHFWSSLSPVAPLSPARL JNK_group 11042694
LTP
1.00
 MOD_ProDKin_1
 - -
0.24
 - medium

Substrate: Glucocorticoid receptor (Transcription factor)
Seq-ID: P04150 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14116   1433S_HUMAN
MINT-3373920   LCK_HUMAN
MINT-3373954   CD4_HUMAN
MINT-3374054   CD3D_HUMAN
MINT-6771456   KS6A5_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding,
glucocorticoid receptor activity,
steroid binding,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
protein binding		 mitochondrial matrix,
nucleus		 transcription from RNA polymerase II promoter,
chromatin modification,
response to protein stimulus,
superior temporal gyrus development,
regulation of transcription, DNA-dependent
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 226 DLLIDENCLLSPLAGEDDSFL JNK_group 12351702
LTP
0.98
 MOD_ProDKin_1
 - GCR
0.34
 - low

Substrate: HSF 1 (Transcription factor)
Seq-ID: Q00613 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-1785958   STUB1_HUMAN
MINT-6743391   STRAP_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding transcription factor activity,
protein binding		 cytoplasm transcription,
regulation of transcription, DNA-dependent
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 363 GHTDTEGRPPSPPPTSTPEKC JNK_group 10747973
LTP
0.47
 MOD_ProDKin_1
 - Vert_HS_TF
0.97
 - high

Substrate: JNK-interacting protein 1 (Transcription factor)
Seq-ID: Q9UQF2 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-14547   A4_HUMAN
MINT-45956   ITB2_HUMAN
MINT-45957   ITB3_HUMAN
MINT-45958   ITB7_HUMAN
MINT-45971   A4_MOUSE
MINT-63239   RECQ5_HUMAN
MINT-74572   EGFR_HUMAN
MINT-74575   ERBB2_HUMAN
MINT-6629291   M3K7_HUMAN
MINT-6629296   MP2K7_HUMAN
MINT-6629301   MK08_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase inhibitor activity,
MAP-kinase scaffold activity,
kinesin binding		 nucleus,
perinuclear region of cytoplasm		 vesicle-mediated transport
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 15 ESGGLGGGAASPPAASPFLGL JNK_group 12756254
LTP
0.91
 MOD_ProDKin_1
 - -
0.66
 - low
S 29 ASPFLGLHIASPPNFRLTHDI JNK_group 12756254
LTP
0.30
 MOD_ProDKin_1
 - -
0.52
 - low
S 197 SWQDRVSRSSSPLKTGEQTPP JNK_group 12756254
LTP
1.00
 MOD_ProDKin_1
 - -
0.93
 - low
T 205 SSSPLKTGEQTPPHEHICLSD JNK_group 12756254
LTP
0.79
 MOD_ProDKin_1
 - -
0.90
 - low
T 284 RLEATEEIYLTPVQRPPDAAE JNK_group 12756254
LTP
1.00
 MOD_ProDKin_1
 - -
0.85
 - low
S 341 EEEEGFDCLSSPERAEPPGGG JNK_group 12756254
LTP
0.16
 MOD_ProDKin_1
 - -
0.81
 - low
S 421 TVYDNCASVSSPYESAIGEEY JNK_group 12756254
LTP
0.06
 MOD_ProDKin_1
 - -
0.47
 - low

Substrate: Shc ( Adaptor molecule)
Seq-ID: P98083 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19712   Q80UM4_MOUSE
MINT-19720   TAXB1_MOUSE
MINT-19873   BRSK1_HUMAN
MINT-45893   ITB1_HUMAN
MINT-45894   ITB2_HUMAN
MINT-45896   ITB7_HUMAN
MINT-58379   GAB1_MOUSE
MINT-5226700   TGFR2_MOUSE
MINT-5226834   TGFR1_MOUSE
MINT-5226862   SOS1_MOUSE
MINT-7714902   IQGA1_HUMAN
MINT-7716148   IQGA1_MOUSE
MINT-7716165   PTN12_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
mitochondrial matrix angiogenesis,
regulation of growth,
actin cytoskeleton reorganization,
heart development,
activation of MAPK activity,
cell-cell adhesion
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 36 SGSTPPEELPSPSASSLGPIL JNK_group 11602589
LTP
0.13
 MOD_ProDKin_1
 - -
0.90
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