a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:	GSK-3 beta (Glycogen synthase kinase-3 beta)
Seq-ID:	P49841 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-65985   DBPA_HUMAN MINT-65986   YBOX1_HUMAN MINT-2837737   PSN1_HUMAN MINT-3974216   TAU_HUMAN MINT-4049759   PCM1_HUMAN MINT-4049773   NIN_HUMAN MINT-4508051   CTNB1_HUMAN MINT-4508259   AXN1_HUMAN MINT-4793253   P53_HUMAN MINT-6761890   PTN1_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process protein serine/threonine kinase activity, tau-protein kinase activity, p53 binding, beta-catenin binding, ATP binding, protein kinase A catalytic subunit binding, NF-kappaB binding Axin-APC-beta-catenin-GSK3B complex, beta-catenin destruction complex, cytosol, nucleus positive regulation of protein catabolic process, hippocampus development, negative regulation of apoptosis, positive regulation of protein export from nucleus, positive regulation of Rac GTPase activity, positive regulation of protein complex assembly, peptidyl-serine phosphorylation, glycogen metabolic process, superior temporal gyrus development, canonical Wnt receptor signaling pathway, ER overload response, negative regulation of protein binding, positive regulation of cell-matrix adhesion
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	216	QLVRGEPNVSYICSRYYRAPE	MAP2K1	15020233	LTP	1.00		-	S_TKc	0.08	1Q5K	79.91%

Substrate:	Mitogen-activated protein kinase 1 (S/T/Y kinase)
Seq-ID:	P28482 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-51440   BCL2_HUMAN MINT-60779   LCK_HUMAN MINT-65987   YBOX1_HUMAN MINT-65988   DBPA_HUMAN MINT-2835582   IEX1_HUMAN MINT-4300420   PEA15_HUMAN MINT-4300484   MP2K1_HUMAN MINT-4301855   CIC_DROME MINT-4329848   CASP8_HUMAN MINT-6613181   MBP_BOVIN MINT-7973774   DLG4_RAT
GO-Terms:	[show] Molecular Function Cellular Component Biological Process DNA binding, ATP binding microtubule cytoskeleton, cytosol, nucleoplasm transcription, cell cycle, chemotaxis, interspecies interaction between organisms, synaptic transmission, Ras protein signal transduction, induction of apoptosis
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
Y	187	DHDHTGFLTEYVATRWYRAPE	MAP2K1	11971971	LTP	1.00		-	S_TKc	0.13	2GPH	81.22%

Substrate:	Mitogen-activated protein kinase 3 (S/T/Y kinase)
Seq-ID:	P27361 [Homo sapiens]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-17608   KSR1_MOUSE MINT-56633   GAB2_HUMAN MINT-4329823   CASP8_HUMAN MINT-7014390   MP2K1_HUMAN MINT-7717318   SQSTM_HUMAN
GO-Terms:	[show] Molecular Function Cellular Component Biological Process ATP binding, MAP kinase activity microtubule cytoskeleton, cytosol, nucleoplasm protein amino acid phosphorylation, cell cycle, interspecies interaction between organisms, Ras protein signal transduction
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	202	DPEHDHTGFLTEYVATRWYRA	MAP2K1	8626767	LTP	1.00		-	S_TKc	0.15	2ZOQ	26.71%
Y	204	EHDHTGFLTEYVATRWYRAPE	MAP2K1	8626767	LTP	1.00		-	S_TKc	0.13	2ZOQ	48.47%

Substrate:	Mitogen-activated protein kinase 3 (S/T/Y kinase)
Seq-ID:	Q63844 [Mus musculus]
Download:	fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):	[show] MINT-15457   MKNK2_MOUSE MINT-17724   MKNK1_MOUSE
GO-Terms:	[show] Molecular Function Cellular Component Biological Process transcription regulator activity, phosphotyrosine binding, ATP binding, MAP kinase activity cytoplasm, nucleoplasm protein amino acid phosphorylation, sensory perception of pain, organ morphogenesis, cartilage development, lipopolysaccharide-mediated signaling pathway, cell cycle, response to exogenous dsRNA, regulation of transcription factor activity, response to DNA damage stimulus
Conservation:
Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	203	DPEHDHTGFLTEYVATRWYRA	MAP2K1	1518847	LTP	1.00		-	S_TKc	0.15	-	low