List of substrates found:


Substrate: Caspase-3 (Cysteine protease CPP32)
Seq-ID: P42574 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 150 TNFFRGDRCRSLTGKPKLFII MAPK14 14970175
LTP
0.98
- CASc
0.11
2J32 20.49%

Substrate: Caspase-8 precursor (Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death)
Seq-ID: Q14790 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 347 TSQFTGLKCPSLAGKPKVFFI MAPK14 14970175
LTP
1.00
- CASc
0.10
1QTN 24.59%

Substrate: Cyclic-AMP-dependent transcription factor ATF-2 (Transcription factor)
Seq-ID: P15336 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 53 DSVIVADQTPTPTRFLKNCEE MAPK14 11971971
LTP
0.00
MOD_ProDKin_1
- -
0.51
--
T 53 DSVIVADQTPTPTRFLKNCEE MAPK14 11896587
LTP
0.00
MOD_ProDKin_1
- -
0.51
--

Substrate: Cytokeratin 8 (keratin, type II cytoskeletal 8 (cytokeratin 8) (K8) (CK8) (from PhosphoBase))
Seq-ID: P05787 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 74 TAVTVNQSLLSPLVLEVDPNI MAPK14 11788583
LTP
0.18
MOD_ProDKin_1
- -
0.28
- low

Substrate: Estrogen receptor alpha (Estrogen receptor (ER) (Estradiol receptor) (ER-alpha); nuclear hormone receptor. )
Seq-ID: P03372 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 311 SKKNSLALSLTADQMVSALLD MAPK14 12138194
LTP
0.27
- -
0.28
2IOG 52.05%

Substrate: ETS domain protein Elk-1 (Transcription factor)
Seq-ID: P19419 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 383 PPSIHFWSTLSPIAPRSPAKL MAPK14 9130707
LTP
1.00
MOD_ProDKin_1
- -
0.43
- medium
S 383 PPSIHFWSTLSPIAPRSPAKL MAPK14 8887554
LTP
1.00
MOD_ProDKin_1
- -
0.43
- medium
S 389 WSTLSPIAPRSPAKLSFQFPS MAPK14 9130707
LTP
0.89
MOD_ProDKin_1
- -
0.46
- medium

Substrate: jdp2 (protein dimerization activity, sequence-specific DNA binding)
Seq-ID: ENSP00000267569 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
sequence-specific DNA binding nucleus transcription
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 148 TCIVRTDSVKTPESEGNPLLE MAPK14 12225289
LTP
1.00
MOD_ProDKin_1
- -
0.63
- low

Substrate: MAP kinase-activated protein kinase 2 (MAP kinase-activated protein kinase 2 (EC 2.7.1.-) (from PhosphoBase))
Seq-ID: P49137 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 25 PAPAPPPQPPTPALPHPPAQP MAPK14 8846784
LTP
0.03
MOD_ProDKin_1
- -
0.95
--
T 222 KETTSHNSLTTPCYTPYYVAP MAPK14 8846784
LTP
0.95
MOD_ProDKin_1
- S_TKc
0.26
2OZA 39.04%
S 272 PFYSNHGLAISPGMKTRIRMG MAPK14 8846784
LTP
1.00
MOD_ProDKin_1
- S_TKc
0.29
1KWP 51.64%
T 334 WIMQSTKVPQTPLHTSRVLKE MAPK14 8846784
LTP
0.93
MOD_ProDKin_1
- -
0.49
2OZA 19.86%

Substrate: MAPKAPK5 (MAP kinase kinase activity, protein serine/threonine kinase activity)
Seq-ID: Q8IW41 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 182 FAKIDQGDLMTPQFTPYYVAP MAPK14 9628874
LTP
0.02
MOD_ProDKin_1
- S_TKc
0.18
- medium

Substrate: Myocyte-specific enhancer factor 2A (Transcription factor)
Seq-ID: Q02078 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 312 SSSQATQPLATPVVSVTTPSL MAPK14 9858528
LTP
1.00
MOD_ProDKin_1
- -
0.70
- medium
T 319 PLATPVVSVTTPSLPPQGLVY MAPK14 9858528
LTP
1.00
MOD_ProDKin_1
- -
0.56
- medium
S 408 QNISIKSEPISPPRDRMTPSG MAPK14 12586839
LTP
1.00
MOD_CDK_SPxK_1
- -
0.88
- medium
S 453 QPQPRQEMGRSPVDSLSSSSS MAPK14 9858528
LTP
1.00
MOD_ProDKin_1
- -
0.95
- medium

Substrate: Myocyte-specific enhancer factor 2C (Myocyte-specific enhancer factor 2C)
Seq-ID: Q06413 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 293 NNSQSAQSLATPVVSVATPTL MAPK14 9069290
LTP
1.00
MOD_ProDKin_1
- -
0.65
--
T 300 SLATPVVSVATPTLPGQGMGG MAPK14 9069290
LTP
1.00
MOD_ProDKin_1
- -
0.63
--

Substrate: Neutrophil cytosol factor 1 (Neutrophil cytosol factor 1)
Seq-ID: P14598 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 345 RRRQARPGPQSPGSPLEEERQ MAPK14 15629715
LTP
0.37
MOD_ProDKin_1
- p47_phox_C
0.92
--
S 348 QARPGPQSPGSPLEEERQTQR MAPK14 15629715
LTP
0.81
MOD_CK2_1
- p47_phox_C
0.94
--

Substrate: NFATC4 (transcription coactivator activity)
Seq-ID: Q14934 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 168 AGAQGGGAFFSPSPGSSSLSS MAPK14 11997522
LTP
0.64
MOD_ProDKin_1
- -
0.65
--
S 170 AQGGGAFFSPSPGSSSLSSWS MAPK14 11997522
LTP
0.64
MOD_ProDKin_1
- -
0.58
--

Substrate: PAK6 (Serine/threonine kinase)
Seq-ID: Q9NQU5 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 165 HKQMPWPEPQSPRVLPNGLAA MAPK14 15550393
LTP
0.07
MOD_ProDKin_1
- -
0.80
--

Substrate: PPARGC-1 alpha (Transcription regulatory protein)
Seq-ID: Q9UBK2 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 263 AKPTTLSLPLTPESPNDPKGS MAPK14 11741533
LTP
1.00
MOD_ProDKin_1
- -
0.89
- medium
S 266 TTLSLPLTPESPNDPKGSPFE MAPK14 11741533
LTP
1.00
MOD_ProDKin_1
- -
0.88
- medium
T 299 SGTAGLTPPTTPPHKANQDNP MAPK14 11741533
LTP
1.00
MOD_ProDKin_1
- -
0.92
- medium

Substrate: Ribosomal protein S6 kinase alpha 4 (Serine/threonine kinase)
Seq-ID: O75676 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 196 FLTEEKERTFSFCGTIEYMAP MAPK14 10806207
LTP
1.00
- S_TKc
0.15
- low
S 343 EEFTRLEPVYSPPGSPPPGDP MAPK14 10806207
LTP
1.00
MOD_ProDKin_1
- S_TK_X
0.70
- low
S 347 RLEPVYSPPGSPPPGDPRIFQ MAPK14 10806207
LTP
0.60
MOD_ProDKin_1
- S_TK_X
0.66
- low
S 360 PGDPRIFQGYSFVAPSILFDH MAPK14 10806207
LTP
1.00
- S_TK_X
0.27
- low
T 568 RPQSPGVPMQTPCFTLQYAAP MAPK14 10806207
LTP
1.00
MOD_ProDKin_1
- S_TKc
0.36
- low

Substrate: RPS6KA5 (serine/threonine kinase)
Seq-ID: O75582 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 360 EEFTEMDPTYSPAALPQSSEK MAPK14 15568999
LTP
1.00
MOD_ProDKin_1
- S_TK_X
0.47
--
T 581 LKPPDNQPLKTPCFTLHYAAP MAPK14 15568999
LTP
1.00
MOD_ProDKin_1
- S_TKc
0.33
--

Substrate: Sam68 (Adapter molecule)
Seq-ID: Q07666 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 58 GGGSRGGARASPATQPPPLLP MAPK14 12478298
LTP
0.11
MOD_ProDKin_1
- -
0.96
- low
T 84 PDATVGGPAPTPLLPPSATAS MAPK14 12478298
LTP
0.27
MOD_ProDKin_1
- -
0.86
- low

Substrate: Sodium/hydrogen exchanger 1 (Membrane transport protein)
Seq-ID: P19634 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
integral to membrane regulation of pH,
sodium ion transport
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 718 YEPKEDLPVITIDPASPQSPE MAPK14 11604491
LTP
0.10
- -
0.78
- medium
S 723 DLPVITIDPASPQSPESVDLV MAPK14 11604491
LTP
1.00
MOD_ProDKin_1
- -
0.73
- medium
S 726 VITIDPASPQSPESVDLVNEE MAPK14 11604491
LTP
0.30
MOD_ProDKin_1
- -
0.73
- medium
S 729 IDPASPQSPESVDLVNEELKG MAPK14 11604491
LTP
0.11
MOD_ProDKin_1
- -
0.75
- medium

Substrate: STAT 4 (Signal transducer and activator of transcription 4)
Seq-ID: P42228 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 722 PQSPSDLLPMSPSAYAVLREN MAPK14 10961885
LTP
0.90
MOD_ProDKin_1
- -
0.49
- low

Substrate: TAK1-binding protein 1 (Possible signaling intermediate between TGFB receptors and MAP3K7/TAK1)
Seq-ID: Q15750 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
catalytic activity,
protein binding
endosome membrane activation of MAPKKK activity
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 423 SQGQMVNGAHSASTLDEATPT MAPK14 14592977
LTP
1.00
- -
0.75
- medium
T 431 AHSASTLDEATPTLTNQSPTL MAPK14 14592977
LTP
0.95
MOD_ProDKin_1
- -
0.77
- medium
S 438 DEATPTLTNQSPTLTLQSTNT MAPK14 14592977
LTP
0.97
MOD_ProDKin_1
- -
0.82
- medium

Substrate: Transcription factor jun-B (Transcription factor)
Seq-ID: P17275 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
GO-Terms:
[show]
Conservation:

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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 79 FSGQGSDTGASLKLASSELER MAPK14 15308641
LTP
0.04
- Jun
0.54
- low

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